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Gene Expression Data
Assay Details
Assay
Reference: J:272568 Munoz-Martin N, et al., Myc is dispensable for cardiomyocyte development but rescues Mycn-deficient hearts through functional replacement and cell competition. Development. 2019 Feb 1;146(3):dev170753
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6403273
Gene symbol: Myc
Gene name: myelocytomatosis oncogene
Reporter: GFP
Antibody: anti-GFP (R1091P)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2C: embryonic day 9.5; Myctm1Slek/Myctm1Slek (more )
Note: Double labeled: green - Myc; red - Acta2 (assay MGI:6403264).
Structure Level Pattern Image Note
TS15: branchial arch Strong 2C right , 2C left , 2C middle
TS15: visceral pericardium Strong 2C right , 2C left , 2C middle
TS15: cardiac muscle tissue Absent 2C left , 2C right , 2C middle
TS15: endocardial lining Present 2C middle , 2C right , 2C left
Specimen 2D: embryonic day 12.5; Myctm1Slek/Myctm1Slek (more )
Structure Level Pattern Image Note
TS20: heart endothelium Present 2D middle , 2D right , 2D left Expressed in endothelial cells within the myocardium.
TS20: visceral pericardium Present Regionally restricted 2D middle , 2D right , 2D left Expressed in the subepicardium.
TS20: endocardial lining Trace 2D middle , 2D left , 2D right mostly absent
TS20: cardiac muscle tissue Absent 2D right , 2D left , 2D middle
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory