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Gene Expression Data
Assay Details
Assay
Reference: J:241980 Guo C, et al., Dkk1 in the peri-cloaca mesenchyme regulates formation of anorectal and genitourinary tracts. Dev Biol. 2014 Jan 01;385(1):41-51
Assay type: RNA in situ
MGI Accession ID: MGI:6401133
Gene symbol: Axin2
Gene name: axin 2
Probe: Axin2 probe18
Probe preparation: Antisense RNA
Results
Specimen 7A: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: genital swelling Weak 7A Low levels of expression in genital fold.
TS18: cloaca associated mesenchyme Weak Regionally restricted 7A Low levels of expression in cloacal mesenchyme.

Specimen 7B: embryonic day 11.0; Dkk1tm1Lmgd/Dkk1tm1Lmgd (more )
Structure Level Pattern Image Note
TS18: genital swelling Strong Regionally restricted 7B Increased overall expression levels in genital fold.
TS18: cloaca associated mesenchyme Strong Regionally restricted 7B Considerably higher expression in dorsal but less so in ventral cloacal mesenchyme than in controls.
TS18: hindlimb bud Strong Regionally restricted 7B Increased expression in posterior edge of hindlimb bud.

Specimen 7C: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: hindlimb bud Present 7C

Specimen 7D: embryonic day 11.0; Dkk1tm1Lmgd/Dkk1tm1Lmgd (more )
Structure Level Pattern Image Note
TS18: hindlimb bud Strong Regionally restricted 7D Increased expression in posterior edge of hindlimb bud.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory