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Gene Expression Data
Assay Details
Assay
Reference: J:284798 Veit M, et al., Mutagenesis of the ADAM17-phosphatidylserine-binding motif leads to embryonic lethality in mice. Life Sci Alliance. 2019 Oct;2(5)
Assay type: Western blot
MGI Accession ID: MGI:6393860
Gene symbol: Adam17
Gene name: a disintegrin and metallopeptidase domain 17
Antibody: anti-Adam17
Detection system: horseradish peroxidase
Results
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified (b) Genetic BackgroundMutant Allele(s)Sex
WT/WT E14.0 (a) TS22: brain Present involves: C57BL/6NTac Not Specified
WT/WT E14.0 (a) TS22: brain Present involves: C57BL/6NTac Not Specified
WT/3x E14.0 (a) TS22: brain Present involves: C57BL/6NTac Adam17em1Krss/Adam17+Not Specified
WT/3x E14.0 (a) TS22: brain Present involves: C57BL/6NTac Adam17em1Krss/Adam17+Not Specified
3x/3x E14.0 (a) TS22: brain Present involves: C57BL/6NTac Adam17em1Krss/Adam17em1KrssNot Specified
3x/3x E14.0 (a) TS22: brain Present involves: C57BL/6NTac Adam17em1Krss/Adam17em1KrssNot Specified
Notes:
(a) Age of embryo at noon of plug day not specified in reference.
(b) Authors report comparable expression of both pro- and mature forms in liver and brains of wild type and mutant embryos.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory