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Gene Expression Data
Assay Details
Assay
Reference: J:275007 Kumar N, et al., The lineage-specific transcription factor CDX2 navigates dynamic chromatin to control distinct stages of intestine development. Development. 2019 Mar 1;146(5):dev172189
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6393629
Gene symbol: Atp4b
Gene name: ATPase, H+/K+ exchanging, beta polypeptide
Antibody: Anti-Atp4b (2B6, D032-3)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 4A Control jejunum: embryonic day 18.5; Cdx2tm1.1Shiv/? (more )
Note: Cre-negative embryos were used as littermate controls.
Structure Level Pattern Image Note
TS26: jejunum Absent 4A ATP4B jejunum Control
Specimen 4A ShhCre;Cdx2f/f jejunum: embryonic day 18.5; Cdx2tm1.1Shiv/Cdx2tm1.1Shiv, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: jejunum Present Regionally restricted 4A ATP4B jejunum ShhCre;Cdx2f/f Ectopic expression was detected anteriorly in the Cdx2-negative jejunum.
Specimen 4A Control ileum: embryonic day 18.5; Cdx2tm1.1Shiv/? (more )
Note: Cre-negative embryos were used as littermate controls.
Structure Level Pattern Image Note
TS26: ileum Absent 4A ATP4B ileum Control
Specimen 4A ShhCre;Cdx2f/f ileum: embryonic day 18.5; Cdx2tm1.1Shiv/Cdx2tm1.1Shiv, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: ileum Absent 4A ATP4B ileum ShhCre;Cdx2f/f
Specimen S4B WT: embryonic day 18.5; Cdx2tm1.1Shiv/? (more )
Note: Cre-negative embryos were used as littermate controls.
Structure Level Pattern Image Note
TS26: stomach glandular region Present Regionally restricted S4B WT ATP4B Expression was detected in the glandular hindstomach.
Specimen S4B Cdx2-/-: embryonic day 18.5; Cdx2tm1.1Shiv/Cdx2tm1.1Shiv (more )
Structure Level Pattern Image Note
TS26: stomach glandular region Present Regionally restricted S4B Cdx2-/- ATP4B Expression was detected in the glandular hindstomach, as in wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory