Gene Expression Image Detail

Reference

Figure

J:275007 Kumar N, et al., Development. 2019 Mar 1;146(5):dev172189

MGI:6393541

Image

Caption

(A) At the top, whole mount images depicting the ShhCreEGFP;Cdx2^f/f phenotype at E18.5. Note the distended intestinal lumen. Below, CDX2 immunostain indicates efficient deletion of Cdx2. A closer look at the ileum of the mutants reveals a keratinized squamous appearance in lieu of the simple columnar epithelium present in the control. (B) Control staining of stomachs from ShhCreEGFP;Cdx2^f/f mutants and controls shows the expected pattern of immunoreactivity for TRP63 in the squamous forestomach, and ATP4B in the glandular hindstomach.

This image is from Kumar N, Development 2019 Mar 1;146(5): and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.

Associated
Assays

Label	Assay & Result Details (Gene Symbol)	Spatial Mapping
A CDX2 left	MGI:6393636 (Cdx2)
A CDX2 right	MGI:6393636 (Cdx2)
B WT TRP63	MGI:6393634 (Trp63)
B WT ATP4B	MGI:6393629 (Atp4b)
B Cdx2-/- TRP63	MGI:6393634 (Trp63)
B Cdx2-/- ATP4B	MGI:6393629 (Atp4b)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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