Htr1b RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:111755 Bonnin A, et al., Expression mapping of 5-HT1 serotonin receptor subtypes during fetal and early postnatal mouse forebrain development. Neuroscience. 2006;141(2):781-794
Assay type:	RNA in situ
MGI Accession ID:	MGI:6392632
Gene symbol:	Htr1b
Gene name:	5-hydroxytryptamine (serotonin) receptor 1B

Probe:	Htr1b cDNA1
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

Specimen 2A: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: caudate-putamen	Present		2A
TS22: globus pallidus	Present		2A

Specimen 2B: embryonic day 14.5 (more

)

Structure	Level	Image	Note
TS22: caudate-putamen	Present	2B
TS22: globus pallidus	Present	2B
TS22: cerebral cortex	Weak	2B	Expression is mostly in the mesocortical perirhinal and insular regions in the lateral cerebral wall.
TS22: hippocampus	Weak	2B

Specimen 2C: embryonic day 14.5 (more

)

Structure	Level	Image	Note
TS22: amygdala	Present	2C
TS22: caudate-putamen	Present	2C
TS22: globus pallidus	Present	2C
TS22: hypothalamus	Present	2C	Expression is in the hypothalamus and is weak in the paraventricular hypothalamic nucleus.
TS22: dorsal thalamus	Weak	2C

Specimen 2D: embryonic day 14.5 (more

)

Structure	Level	Image
TS22: amygdala	Present	2D
TS22: caudate-putamen	Present	2D
TS22: dorsal lateral geniculate nucleus	Present	2D
TS22: globus pallidus	Present	2D
TS22: hypothalamus	Present	2D
TS22: dorsal thalamus	Weak	2D

Specimen 2E: embryonic day 16.5 (more

)

Structure	Level	Pattern	Image	Note
TS24: caudate-putamen	Present		2E
TS24: globus pallidus	Present		2E

Specimen 2F: embryonic day 16.5 (more

)

Structure	Level	Pattern	Image	Note
TS24: caudate-putamen	Present		2F
TS24: globus pallidus	Present		2F
TS24: main olfactory bulb	Present	Regionally restricted	2F	Expression is in the nucleus of the lateral olfactory tract.
TS24: cerebral cortex	Weak		2F	Expression is mostly in the mesocortical perirhinal and insular regions in the lateral cerebral wall.

Specimen 2G: embryonic day 16.5 (more

)

Structure	Level	Image	Note
TS24: amygdala	Present	2G
TS24: caudate-putamen	Present	2G
TS24: globus pallidus	Present	2G
TS24: paraventricular hypothalamic nucleus	Present	2G
TS24: hippocampus	Present	2G	Expression is stronger in the CA1/CA3 region.
TS24: ganglionic eminence	Absent	2G

Specimen 2H: embryonic day 16.5 (more

)

Structure	Level	Image	Note
TS24: amygdala	Present	2H
TS24: caudate-putamen	Present	2H
TS24: globus pallidus	Present	2H
TS24: reticular thalamic nucleus	Present	2H
TS24: zona incerta	Present	2H
TS24: dorsal lateral geniculate nucleus	Strong	2H
TS24: dorsal thalamus	Strong	2H
TS24: hypothalamus	Strong	2H
TS24: hippocampus	Present	2H	Expression is stronger in the CA1/CA3 region.

Specimen 2I: postnatal day 0 (more

)

Structure	Level	Image
TS27: caudate-putamen	Strong	2I
TS27: cortical plate	Strong	2I
TS27: globus pallidus	Present	2I

Specimen 2J: postnatal day 0 (more

)

Structure	Level	Image	Note
TS27: caudate-putamen	Strong	2J
TS27: hippocampus CA1	Strong	2J
TS27: hippocampus CA3	Strong	2J
TS27: globus pallidus	Present	2J
TS27: nucleus of lateral olfactory tract	Present	2J
TS27: cortical plate	Strong	2J	Highest expression are in the lateral mesocortical areas including the mid- and posterior insular and perirhinal regions.

Specimen 2K: postnatal day 0 (more

)

Structure	Level	Image
TS27: caudate-putamen	Strong	2K
TS27: cortical plate	Strong	2K
TS27: hippocampus CA1	Strong	2K
TS27: hippocampus CA3	Strong	2K
TS27: globus pallidus	Present	2K
TS27: paraventricular hypothalamic nucleus	Weak	2K

Specimen 2L: postnatal day 0 (more

)

Structure	Level	Pattern	Image	Note
TS27: anterior dorsal thalamic nucleus	Very strong		2L
TS27: nucleus reuniens	Very strong		2L
TS27: paraventricular thalamic nucleus	Very strong		2L
TS27: ventral posterior lateral thalamic nucleus	Very strong		2L
TS27: ventral posterior medial thalamic nucleus	Very strong		2L
TS27: thalamic nucleus	Very strong	Regionally restricted	2L	Expression is in the ventromedial thalamic nucleus.
TS27: caudate-putamen	Strong		2L
TS27: cortical plate	Strong		2L
TS27: hippocampus CA1	Strong		2L
TS27: hippocampus CA3	Strong		2L
TS27: hypothalamus	Strong		2L
TS27: reticular thalamic nucleus	Strong		2L
TS27: zona incerta	Strong		2L
TS27: globus pallidus	Present		2L
TS27: amygdala	Weak		2L
TS27: dorsal lateral geniculate nucleus	Weak		2L

Specimen 6B: embryonic day 16.5 (more

)

Structure	Level	Image	Note
TS24: ventral lateral thalamic nucleus	Strong	6B
TS24: ventral posterior lateral thalamic nucleus	Strong	6B
TS24: ventral posterior medial thalamic nucleus	Strong	6B
TS24: dorsal thalamus	Strong	6B	Expression includes posterior thalamic nuclei.

Specimen not shown: embryonic day 12.5 (more

)

Structure	Level	Pattern	Image	Note
TS20: hypothalamus	Trace

Specimen Table 2 E14.5: embryonic day 14.5 (more

)

Structure	Level	Pattern	Note
TS22: amygdala	Present
TS22: caudate-putamen	Present
TS22: cortical plate	Present
TS22: dorsal lateral geniculate nucleus	Present
TS22: globus pallidus	Present
TS22: lateral habenular nucleus	Present
TS22: lateral preoptic area	Present
TS22: medial habenular nucleus	Present
TS22: piriform cortex	Present
TS22: ventral posterior lateral thalamic nucleus	Present
TS22: ventral posterior medial thalamic nucleus	Present
TS22: thalamic nucleus	Present		Includes the ventrolateral thalamic nucleus, ventromedial thalamic nucleus, and the posterior complex.
TS22: hypothalamus	Present		Expression is in the paraventricular hypothalamic nucleus.
TS22: hypothalamus medial zone	Present	Regionally restricted	Expression is in the medial preoptic area.

Specimen Table 2 E16.5: embryonic day 16.5 (more

)

Structure	Level	Pattern	Note
TS24: amygdala	Present
TS24: caudate-putamen	Present
TS24: cortical plate	Present
TS24: dorsal lateral geniculate nucleus	Present
TS24: globus pallidus	Present
TS24: hippocampus	Present
TS24: lateral habenular nucleus	Present
TS24: medial habenular nucleus	Present
TS24: paraventricular hypothalamic nucleus	Present
TS24: paraventricular thalamic nucleus	Present
TS24: piriform cortex	Present
TS24: ventral lateral thalamic nucleus	Present
TS24: ventral posterior lateral thalamic nucleus	Present
TS24: ventral posterior medial thalamic nucleus	Present
TS24: hippocampal formation	Present	Regionally restricted	Expression is in the dentate gyrus.
TS24: thalamic nucleus	Present		Includes the ventromedial thalamic nucleus and posterior complex.
TS24: diencephalon	Present	Regionally restricted	Expression is in the nucleus of lateral olfactory tract.

Specimen Table 2 P0: postnatal day 0 (more

)

Structure	Level	Note
TS27: amygdala	Present
TS27: caudate-putamen	Present
TS27: cortical layer V	Present
TS27: cortical layer VI	Present
TS27: cortical plate	Present
TS27: dentate gyrus	Present
TS27: dorsal lateral geniculate nucleus	Present
TS27: globus pallidus	Present
TS27: hippocampus	Present
TS27: lateral habenular nucleus	Present
TS27: medial habenular nucleus	Present
TS27: nucleus of lateral olfactory tract	Present
TS27: paraventricular hypothalamic nucleus	Present
TS27: paraventricular thalamic nucleus	Present
TS27: piriform cortex	Present
TS27: reticular thalamic nucleus	Present
TS27: ventral lateral thalamic nucleus	Present
TS27: ventral posterior lateral thalamic nucleus	Present
TS27: ventral posterior medial thalamic nucleus	Present
TS27: zona incerta	Present
TS27: thalamic nucleus	Present	Expression is in the ventromedial thalamic nucleus and the posterior complex.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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