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Gene Expression Data
Assay Details
Assay
Reference: J:139570 Capellini TD, et al., Pbx1/Pbx2 govern axial skeletal development by controlling Polycomb and Hox in mesoderm and Pax1/Pax9 in sclerotome. Dev Biol. 2008 Sep 15;321(2):500-14
Assay type: RNA in situ
MGI Accession ID: MGI:6391086
Gene symbol: Shh
Gene name: sonic hedgehog
Probe: Shh cDNA3
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen E9.5 Shh WT not shown: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: notochord Present
Specimen E9.5 Shh Pbx1-/-;Pbx2+/- not shown: embryonic day 9.5; Pbx1tm1Mlc/Pbx1tm1Mlc, Pbx2tm1Mlc/Pbx2+ (more )
Structure Level Pattern Image Note
TS15: notochord Present Expression remained normal in notochord.
Specimen E10.5 Shh WT not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: notochord Present
Specimen E10.5 Shh Pbx1-/-;Pbx2+/- not shown: embryonic day 10.5; Pbx1tm1Mlc/Pbx1tm1Mlc, Pbx2tm1Mlc/Pbx2+ (more )
Structure Level Pattern Image Note
TS17: notochord Present Expression remained normal in notochord.
Specimen 4B Shh FL WT: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: neural tube floor plate Present 4B Shh FL WT
TS19: notochord Present 4B Shh FL WT
Specimen 4B Shh FL Pbx1-/-;Pbx2+/-: embryonic day 11.5; Pbx1tm1Mlc/Pbx1tm1Mlc, Pbx2tm1Mlc/Pbx2+ (more )
Structure Level Pattern Image Note
TS19: neural tube floor plate Present 4B Shh FL Pbx1-/-;Pbx2+/- Expression unaltered in notchord and neural floor plate at level of forelimb.
TS19: notochord Present 4B Shh FL Pbx1-/-;Pbx2+/- Expression unaltered in notchord and neural floor plate at level of forelimb.
Specimen 4B Shh HL WT: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: neural tube floor plate Present 4B Shh HL WT
TS19: notochord Present 4B Shh HL WT
Specimen 4B Shh HL Pbx1-/-;Pbx2+/-: embryonic day 11.5; Pbx1tm1Mlc/Pbx1tm1Mlc, Pbx2tm1Mlc/Pbx2+ (more )
Structure Level Pattern Image Note
TS19: neural tube floor plate Present 4B Shh HL Pbx1-/-;Pbx2+/- Expression unaltered in notchord and neural floor plate at level of forelimb.
TS19: notochord Present 4B Shh HL Pbx1-/-;Pbx2+/- Expression unaltered in notchord and neural floor plate at level of forelimb.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory