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Gene Expression Data
Assay Details
Assay
Reference: J:239146 Mademtzoglou D, et al., A p57 conditional mutant allele that allows tracking of p57-expressing cells. Genesis. 2017 Apr;55(4)
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6390900
Gene symbol: Cdkn1c
Gene name: cyclin dependent kinase inhibitor 1C
Reporter: lacZ
Direct Detection
Assay notes: Heterozygote animals with maternally transmitted transgene were used.
Results
Specimen 2A: embryonic day 10.5; Cdkn1ctm1Ins/Cdkn1c+ (more )
Structure Level Pattern Image Note
TS17: brain Strong 2A
TS17: heart Strong 2A
TS17: somite Strong 2A
TS17: limb Strong Regionally restricted 2A Expression is concentrated in central masses in differentiating muscle and skeletal cells.
TS17: ear Present 2A
TS17: lens vesicle Present 2A
TS17: nasal process Present 2A
Specimen 2B: embryonic day 11.5; Cdkn1ctm1Ins/Cdkn1c+ (more )
Structure Level Pattern Image Note
TS19: brain Strong 2B
TS19: heart Strong 2B
TS19: somite Strong 2B
TS19: limb Strong Regionally restricted 2B Expression is concentrated in central masses in differentiating muscle and skeletal cells.
TS19: ear Present 2B
TS19: lens vesicle Present 2B
TS19: nasal process Present 2B
Specimen 2C: embryonic day 12.5; Cdkn1ctm1Ins/Cdkn1c+ (more )
Structure Level Pattern Image Note
TS20: limb Strong 2C
TS20: limb digit Strong 2C
TS20: embryo Present Widespread 2C Expression covers almost the entire exterior of the embryos.
TS20: skin Present Widespread 2C Expression covers almost the entire exterior of the embryos.
Specimen 2D: embryonic day 13.5; Cdkn1ctm1Ins/Cdkn1c+ (more )
Structure Level Pattern Image Note
TS21: limb Strong 2D
TS21: limb digit Strong 2D
TS21: embryo Present Widespread 2D Expression covers almost the entire exterior of the embryos.
TS21: skin Present Widespread 2D Expression covers almost the entire exterior of the embryos.
Specimen 2E: embryonic day 14.5; Cdkn1ctm1Ins/Cdkn1c+ (more )
Structure Level Pattern Image Note
TS22: embryo Present Widespread 2E Expression covers almost the entire exterior of the embryos.
TS22: skin Present Widespread 2E Expression covers almost the entire exterior of the embryos.
Specimen 2F: embryonic day 15.5; Cdkn1ctm1Ins/Cdkn1c+ (more )
Structure Level Pattern Image Note
TS23: skin Present Widespread 2F Expression covers almost the entire exterior of the embryos.
Specimen 2G: embryonic day 16.5; Cdkn1ctm1Ins/Cdkn1c+ (more )
Structure Level Pattern Image Note
TS24: skin Present Widespread 2G Expression covers almost the entire exterior of the embryos.
Specimen 2H: embryonic day 17.5; Cdkn1ctm1Ins/Cdkn1c+ (more )
Structure Level Pattern Image Note
TS25: skin Present Widespread 2H Expression covers almost the entire exterior of the embryos.
Specimen 2K: embryonic day 13.5; Cdkn1ctm1Ins/Cdkn1c+ (more )
Structure Level Pattern Image Note
TS21: body wall Present 2K
TS21: dorsal root ganglion Present 2K
TS21: heart Present 2K
TS21: limb musculature Present 2K
TS21: lung Present 2K
TS21: spinal cord Present 2K
TS21: thoracic vertebral cartilage condensation Present 2K
Specimen 3A: postnatal week 8-12; Cdkn1ctm1Ins/Cdkn1c+ (more )
Structure Level Pattern Image Note
TS28: glomerular tuft Present 3A
Specimen 3A': postnatal week 8-12; Cdkn1ctm1Ins/Cdkn1c+ (more )
Structure Level Pattern Image Note
TS28: glomerular tuft Present 3A'
Specimen 3B: postnatal week 8-12; Cdkn1ctm1Ins/Cdkn1c+ (more )
Structure Level Pattern Image Note
TS28: seminiferous tubule Present 3B
Specimen 3B': postnatal week 8-12; Cdkn1ctm1Ins/Cdkn1c+ (more )
Structure Level Pattern Image Note
TS28: seminiferous tubule Present 3B'
Specimen 3C: postnatal week 8-12; Cdkn1ctm1Ins/Cdkn1c+ (more )
Structure Level Pattern Image Note
TS28: skeletal muscle Present 3C
Specimen 3C': postnatal week 8-12; Cdkn1ctm1Ins/Cdkn1c+ (more )
Structure Level Pattern Image Note
TS28: skeletal muscle Present 3C'
Specimen 3D: postnatal week 8-12; Cdkn1ctm1Ins/Cdkn1c+ (more )
Structure Level Pattern Image Note
TS28: salivary gland Present 3D
Specimen 3D': postnatal week 8-12; Cdkn1ctm1Ins/Cdkn1c+ (more )
Structure Level Pattern Image Note
TS28: salivary gland Present 3D'
Specimen 3E: postnatal week 8-12; Cdkn1ctm1Ins/Cdkn1c+ (more )
Structure Level Pattern Image Note
TS28: heart Present 3E
Specimen 3F: postnatal week 8-12; Cdkn1ctm1Ins/Cdkn1c+ (more )
Structure Level Pattern Image Note
TS28: brain Present 3F
Specimen 3G: postnatal week 8-12; Cdkn1ctm1Ins/Cdkn1c+ (more )
Structure Level Pattern Image Note
TS28: intestine Present 3G
Specimen 3H: postnatal week 8-12; Cdkn1ctm1Ins/Cdkn1c+ (more )
Structure Level Pattern Image Note
TS28: lung Present 3H
Specimen 4A: embryonic day 13.5; Cdkn1ctm1Ins/Cdkn1c+ (more )
Structure Level Pattern Image Note
TS21: thoracic vertebral cartilage condensation Present 4A
Specimen 4B: embryonic day 13.5; Cdkn1ctm1Ins/Cdkn1c+ (more )
Structure Level Pattern Image Note
TS21: forelimb cartilage condensation Present 4B
Specimen 4C: embryonic day 13.5; Cdkn1ctm1Ins/Cdkn1c+ (more )
Structure Level Pattern Image Note
TS21: heart Present 4C
Specimen 4D: embryonic day 13.5; Cdkn1ctm1Ins/Cdkn1c+ (more )
Structure Level Pattern Image Note
TS21: body wall Present 4D
Specimen S1 A: embryonic day 12.5; Cdkn1ctm1Ins/Cdkn1c+ (more )
Structure Level Pattern Image Note
TS20: embryo Present S1A
Specimen S1 B: embryonic day 14.5; Cdkn1ctm1Ins/Cdkn1c+ (more )
Structure Level Pattern Image Note
TS22: embryo Present S1B
Specimen S1 C: postnatal adult; Cdkn1ctm1Ins/Cdkn1c+ (more )
Structure Level Pattern Image Note
TS28: metanephros Present S1C
Specimen S1 D: postnatal adult; Cdkn1ctm1Ins/Cdkn1c+ (more )
Structure Level Pattern Image Note
TS28: heart Present S1D
Specimen not shown: postnatal week 8-12; Cdkn1ctm1Ins/Cdkn1c+ (more )
Structure Level Pattern Image Note
TS28: liver Absent
TS28: spleen Absent
Specimen S2 lens: postnatal day 0; Cdkn1ctm1Ins/Cdkn1c+ (more )
Structure Level Pattern Image Note
TS27: lens Present S2_ lens p57FL-ILZ(m)/+
Specimen S2 lens cKO: postnatal day 0; Cdkn1ctm1.1Ins/Cdkn1c+, Tg(Pgk1-cre)1Lni/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: lens Trace S2_lens p57cKO(m)/+
Specimen S2 kidney: postnatal day 0; Cdkn1ctm1Ins/Cdkn1c+ (more )
Structure Level Pattern Image Note
TS27: glomerular tuft Present S2_ kidney p57FL-ILZ(m)/+
Specimen S2 kidney cKO: postnatal day 0; Cdkn1ctm1.1Ins/Cdkn1c+, Tg(Pgk1-cre)1Lni/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: glomerular tuft Trace S2_kidney p57cKO(m)/+
Specimen S2 body wall: embryonic day 13.5; Cdkn1ctm1Ins/Cdkn1c+ (more )
Structure Level Pattern Image Note
TS21: body wall Present S2_ body wall p57FL-ILZ(m)/+
Specimen S2 body wall cKO: embryonic day 13.5; Cdkn1ctm1.1Ins/Cdkn1c+, Tg(Pgk1-cre)1Lni/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: body wall Trace S2_body wall p57cKO(m)/+
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory