Cdkn1c^tm1Ins
Targeted Allele Detail

Summary

• Symbol: Cdkn1c^tm1Ins
• Name: cyclin dependent kinase inhibitor 1C; targeted mutation 1, INSERM
• MGI ID: MGI:6390816
• Synonyms: p57^FL-N-ILZ
• Gene: Cdkn1c Location: Chr7:143012076-143014735 bp, - strand Genetic Position: Chr7, 88.22 cM
• Alliance: Cdkn1c^tm1Ins page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:239146
• Parent Cell Line: CK35 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Conditional ready, Reporter)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2. A loxP site, FRT-flanked neomycin resistance cassette,, IRES sequence, polyadenylation sequence, and lacZ reporter gene replaced the non-coding exon 4. (J:239146)

Expression

In Mice Carrying this Mutation:

67 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cdkn1c Mutation: 19 strains or lines available

References

• Original: J:239146 Mademtzoglou D, et al., A p57 conditional mutant allele that allows tracking of p57-expressing cells. Genesis. 2017 Apr;55(4)
• All: 1 reference(s)