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Gene Expression Data
Assay Details
Assay
Reference: J:231098 Theveniau-Ruissy M, et al., Coronary stem development in wild-type and Tbx1 null mouse hearts. Dev Dyn. 2016 Apr;245(4):445-59
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6389817
Gene symbol: Tbx1
Gene name: T-box 1
Reporter: lacZ
Direct Detection
Assay notes: X-gal staining.
Results
Specimen 5A upper left: embryonic day 12.5; Tbx1tm1Bld/Tbx1+ (more )
Structure Level Pattern Image Note
TS20: myocardium layer Present Regionally restricted 5A upper left Expressed in cardiomyocytes surrounding the left but not right proximal coronary artery.
TS20: ascending aorta Present Regionally restricted 5A upper left Expressed in endothelial cells.
TS20: pulmonary trunk Present Regionally restricted 5A upper left Expressed in endothelial cells.
TS20: coronary vascular plexus Present Regionally restricted 5A upper left Expressed in endothelial cells.

Specimen 5A upper right: embryonic day 12.5; Tbx1tm1Bld/Tbx1+ (more )
Structure Level Pattern Image Note
TS20: myocardium layer Present Regionally restricted 5A upper right Expressed in cardiomyocytes surrounding the left but not right proximal coronary artery.
TS20: ascending aorta Present Regionally restricted 5A upper right Expressed in endothelial cells.
TS20: coronary vascular plexus Present Regionally restricted 5A upper right Expressed in endothelial cells.
TS20: pulmonary trunk Present Regionally restricted 5A upper right Expressed in endothelial cells.

Specimen 5A lower: embryonic day 13.5; Tbx1tm1Bld/Tbx1+ (more )
Note: Double labeled: blue - Tbx1 reporter; purple - Pecam1 (assay MGI:6389819).
Structure Level Pattern Image Note
TS21: myocardium layer Present Regionally restricted 5A lower left , 5A lower right Expressed in cardiomyocytes surrounding the left proximal coronary artery.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory