Serpine2 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:16551 Mansuy IM, et al., Variable and multiple expression of Protease Nexin-1 during mouse organogenesis and nervous system development. Development. 1993 Dec;119(4):1119-34
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6389015
Gene symbol:	Serpine2
Gene name:	serine (or cysteine) peptidase inhibitor, clade E, member 2

Antibody:	anti-rat PN-1 (4B3)
Detection system:	Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Assay notes:	Specimens were fixed in Cryofix solution and microwaved.

Results

3A ©

Specimen 3A: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: liver	Present	Single cells	3A	Expression is rare in an occasional cell.

3B ©

Specimen 3B: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: tongue intrinsic muscle	Present	Regionally restricted	3B	Expression is in proliferating myoblasts and is mostly absent in myotubes.

3C ©

Specimen 3C: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: olfactory epithelium	Absent		3C

3D ©

Specimen 3D: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: maturing renal corpuscle	Present	Regionally restricted	3D	Expression is in primitive glomeruli dispersed throughout.

3E ©

Specimen 3E: embryonic day 14.5 (more

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Structure	Level	Pattern	Image	Note
TS22: bronchiole	Present	Single cells	3E

3F ©

Specimen 3F: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: skin	Strong	Regionally restricted	3F	Expression is in the basal lamina.

3G ©

Specimen 3G: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: midbrain	Present	Regionally restricted	3G	Expression is in axon bundles.
TS22: cerebral cortex	Present	Regionally restricted	3G	Expression is in axons from layer V cortical neurons projecting subcortically.

3H ©

Specimen 3H: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: cartilage	Strong		3H

3I ©

Specimen 3I: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: cartilage	Strong		3I
TS22: bone	Absent		3I

6G ©

Specimen 6G: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: main olfactory bulb glomerular layer	Present		6G
TS28: main olfactory bulb mitral cell layer	Absent		6G

6H ©

Specimen 6H: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: accessory olfactory bulb glomerular layer	Present		6H
TS28: main olfactory bulb mitral cell layer	Absent		6H

8A ©

Specimen 8A: postnatal day 7 (more

)

Structure	Level	Pattern	Image	Note
TS28: cortical layer V	Present		8A	Expression is in pyramidal cells.

8B ©

Specimen 8B: postnatal day 7 (more

)

Structure	Level	Pattern	Image	Note
TS28: intercerebral commissure	Present	Regionally restricted	8B	Expression is in layers next to the corpus callosum.

8C ©

Specimen 8C: postnatal day 7 (more

)

Structure	Level	Pattern	Image	Note
TS28: globus pallidus	Present		8C

8D ©

Specimen 8D: postnatal day 7 (more

)

Structure	Level	Pattern	Image	Note
TS28: hippocampus	Present		8D

8E ©

Specimen 8E: postnatal day 21 (more

)

Structure	Level	Pattern	Image	Note
TS28: hippocampus	Absent		8E

8F ©

Specimen 8F: postnatal day 11 (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebellum Purkinje cell layer	Present		8F

8G ©

Specimen 8G: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: cortical layer V	Present	Regionally restricted	8G	Expression is in pyramidal cells.

8I ©

Specimen 8I: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: corpus striatum	Present		8I	Expression is in the striatum with a few highly positive cells in the matrix compartment.

9C c ©

Specimen 9C c: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: seminal fluid	Present		9C c

9C d ©

Specimen 9C d: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: epithelium of seminal vesicle	Present		9C d	Expression is at the apical surface of the epithelial cells.

9C e ©

Specimen 9C e: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: interstitium of the testis	Present	Regionally restricted	9C e	Expression is in the interstitial cells between the seminiferous tubules

Specimen not shown P2: postnatal day 2 (more

)

Structure	Level	Pattern	Note
TS27: cortical layer V	Present		Expression is in pyramidal neurons.
TS27: brainstem	Present	Regionally restricted
TS27: cerebellum	Present	Regionally restricted
TS27: corpus striatum	Present	Regionally restricted
TS27: deep cerebellar nucleus	Present	Regionally restricted
TS27: inferior colliculus	Present	Regionally restricted
TS27: substantia nigra	Present	Regionally restricted
TS27: superior colliculus	Present	Regionally restricted
TS27: thalamus	Present	Regionally restricted
TS27: basal forebrain	Present	Regionally restricted	Expression is in subsets of cells in the diagonal band of Broca.

Specimen not shown Adult: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebellum Purkinje cell layer	Present	Single cells		Expression is in an occasional Purkinje cell.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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