Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Krt19-icre)2Hirt
Name:	transgene insertion 2, Hiroyuki Tomita
MGI ID:	MGI:6387216
Synonyms:	Krt19-iCre#2
Transgene:	Tg(Krt19-icre)2Hirt  Location: unknown
Alliance:	Tg(Krt19-icre)2Hirt page

Strain of Origin:

B6D2F1

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Krt19-icre)2Hirt expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Krt19 (MGI:96693)   Mutation details: Using bacterial recombineering technology, BAC RP24-68P2 containing the entire Krt19 was used to generate a transgene with a iCre-polyA cassette replacing the ATG codon and the following 632 bps of the coding sequence in the Krt19 gene. Twelve founder lines were generated. Line 2 and 5 heterozygous showed no health issue, and the line #2 was used for the studies. (J:279102)

Activity:	Tissue activity of this recombinase allele
Driver:	Krt19 (mouse) Summary of all recombinase alleles driven by Krt19. Comparative matrix view of recombinase activities Alliance mouse Krt19 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:279102 Kanayama T, et al., Characterization of a BAC transgenic mouse expressing Krt19-driven iCre recombinase in its digestive organs. PLoS One. 2019;14(8):e0220818
All:	2 reference(s)