Six3 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:136711 Zhao H, et al., Fibroblast growth factor receptor signaling is essential for lens fiber cell differentiation. Dev Biol. 2008 Jun 15;318(2):276-88
Assay type:	RNA in situ
MGI Accession ID:	MGI:6386995
Gene symbol:	Six3
Gene name:	sine oculis-related homeobox 3

Probe:	Six3 probe10
Probe preparation:	labelled with S35

Results

3Q ©

Specimen 3Q: embryonic day 11.5; Fgfr1^tm1Jpa/Fgfr1^tm1Jpa, Fgfr2^tm1Dor/Fgfr2^tm1Dor, Fgfr3^tm1Dor/Fgfr3^tm1Dor, Tg(Cryaa-cre)10Mlr/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS19: lens vesicle	Present	Uniform	3Q	Expression at similar levels in all lens cells.

3R ©

Specimen 3R: embryonic day 11.5; Fgfr1^tm1Jpa/Fgfr1^tm1Jpa, Fgfr2^tm1Dor/Fgfr2^tm1Dor (more

)

Structure	Level	Pattern	Image	Note
TS19: lens vesicle epithelium	Present		3R

3S ©

Specimen 3S: embryonic day 12.5; Fgfr1^tm1Jpa/Fgfr1^tm1Jpa, Fgfr2^tm1Dor/Fgfr2^tm1Dor, Fgfr3^tm1Dor/Fgfr3^tm1Dor, Tg(Cryaa-cre)10Mlr/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS21: lens	Present	Uniform	3S	Expression at similar levels in all lens cells.

3T ©

Specimen 3T: embryonic day 12.5; Fgfr1^tm1Jpa/Fgfr1^tm1Jpa, Fgfr2^tm1Dor/Fgfr2^tm1Dor (more

)

Structure	Level	Pattern	Image	Note
TS21: lens epithelium	Present		3T
TS21: posterior lens fiber	Weak	Regionally restricted	3T	Decreased expression in elongating primary fiber cells.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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