Ccnd2 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:136711 Zhao H, et al., Fibroblast growth factor receptor signaling is essential for lens fiber cell differentiation. Dev Biol. 2008 Jun 15;318(2):276-88
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6386987
Gene symbol:	Ccnd2
Gene name:	cyclin D2

Antibody:

Results

4E ©

Specimen 4E: embryonic day 12.5; Fgfr1^tm1Jpa/Fgfr1^tm1Jpa, Fgfr2^tm1Dor/Fgfr2^tm1Dor, Fgfr3^tm1Dor/Fgfr3^tm1Dor, Tg(Cryaa-cre)10Mlr/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS21: lens	Present		4E	Authors report the expression in the posterior of mutant lenses was at a level close to that observed in equatorial lens fiber cells of control lenses.

4F ©

Specimen 4F: embryonic day 12.5; Fgfr1^tm1Jpa/Fgfr1^tm1Jpa, Fgfr2^tm1Dor/Fgfr2^tm1Dor (more

)

Structure	Level	Image	Note
TS21: lens anterior epithelium	Strong	4F	High levels of expression in anterior epithelium and equatorial lens fiber cells.
TS21: posterior lens fiber	Strong	4F	High levels of expression in anterior epithelium and equatorial lens fiber cells.
TS21: anterior lens fiber	Weak	4F	Reduced levels of expression in more mature lens fiber cells.

4G ©

Specimen 4G: embryonic day 16.5; Fgfr1^tm1Jpa/Fgfr1^tm1Jpa, Fgfr2^tm1Dor/Fgfr2^tm1Dor, Fgfr3^tm1Dor/Fgfr3^tm1Dor, Tg(Cryaa-cre)10Mlr/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS24: lens	Weak	Widespread	4G	Weak expression throughout the lens.

4H ©

Specimen 4H: embryonic day 16.5; Fgfr1^tm1Jpa/Fgfr1^tm1Jpa, Fgfr2^tm1Dor/Fgfr2^tm1Dor (more

)

Structure	Level	Pattern	Image	Note
TS24: lens epithelium	Weak		4H	Expression restricted to lens epithelium.
TS24: lens fiber	Absent		4H

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