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Gene Expression Data
Assay Details
Assay
Reference: J:103587 Oxburgh L, et al., BMP4 substitutes for loss of BMP7 during kidney development. Dev Biol. 2005 Oct 15;286(2):637-46
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6386721
Gene symbol: Bmp7
Gene name: bone morphogenetic protein 7
Reporter: lacZ
Direct Detection
Assay notes: The fixative was 0.5% glutaraldehyde, 1% paraformaldehyde.
Results
Specimen 4A: embryonic day 14.5; Bmp7tm2Rob/Bmp7+ (more )
Structure Level Pattern Image Note
TS22: mesenchyme of metanephros Present Regionally restricted 4A Expression is in the nephrogenic mesenchyme.
TS22: collecting duct Present 4A
TS22: cortical early distal tubule Present 4A
TS22: early nephron Present 4A
TS22: Bowman's capsule of maturing renal corpuscle Present Regionally restricted 4A Expression is in podocytes.

Specimen 4A': embryonic day 14.5; Bmp7tm2Rob/Bmp7+ (more )
Structure Level Pattern Image Note
TS22: mesenchyme of metanephros Present Regionally restricted 4A' Expression is in the nephrogenic mesenchyme.
TS22: collecting duct Present 4A'
TS22: cortical early distal tubule Present 4A'
TS22: early nephron Present 4A'
TS22: Bowman's capsule of maturing renal corpuscle Present Regionally restricted 4A' Expression is in podocytes.

Specimen 4B: embryonic day 14.5; Bmp7tm2Rob/Bmp7tm2Rob (more )
Structure Level Pattern Image Note
TS22: metanephros Present 4B Expression is in the abnormally developed deformed kidney.

Specimen 4B': embryonic day 14.5; Bmp7tm2Rob/Bmp7tm2Rob (more )
Structure Level Pattern Image Note
TS22: metanephros Present 4B' Expression is in the abnormally developed deformed kidney.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory