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Gene Expression Data
Assay Details
Assay
Reference: J:272619 Aydogdu N, et al., TBX2 and TBX3 act downstream of canonical WNT signaling in patterning and differentiation of the mouse ureteric mesenchyme. Development. 2018 Nov 26;145(23):dev171827
Assay type: RNA in situ
MGI Accession ID: MGI:6385865
Gene symbol: Shisa2
Gene name: shisa family member 2
Probe: Shisa2 probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 6E WT E13.5: embryonic day 13.5; Tbx2tm2.2Vmc/?, Tbx3tm3.2Moon/?, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Structure Level Pattern Image Note
TS21: ureteral mesenchyme Present Regionally restricted 6E WT E13.5 Shisa2 Expression was detected in the inner region of the ureteric mesenchyme.
Specimen 6E Tbx2/3cDKO E13.5: embryonic day 13.5; Tbx2tm2.2Vmc/Tbx2tm2.2Vmc, Tbx3tm3.2Moon/Tbx3tm3.2Moon, Tbx18tm4(cre)Akis/Tbx18+, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: ureteral mesenchyme Present 6E Tbx2/3cDKO E13.5 Shisa2
Specimen 6E WT E14.5: embryonic day 14.5; Tbx2tm2.2Vmc/?, Tbx3tm3.2Moon/?, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Structure Level Pattern Image Note
TS22: ureteral mesenchyme Present Regionally restricted 6E WT E14.5 Shisa2 Expression was detected in the inner region of the ureteric mesenchyme.
Specimen 6E Tbx2/3cDKO E14.5: embryonic day 14.5; Tbx2tm2.2Vmc/Tbx2tm2.2Vmc, Tbx3tm3.2Moon/Tbx3tm3.2Moon, Tbx18tm4(cre)Akis/Tbx18+, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: ureteral mesenchyme Present 6E Tbx2/3cDKO E14.5 Shisa2 Expression was upregulated at E14.5 in the conditional mutant.
Specimen 6E WT E18.5: embryonic day 18.5; Tbx2tm2.2Vmc/?, Tbx3tm3.2Moon/?, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Structure Level Pattern Image Note
TS26: ureter Present 6E WT E18.5 Shisa2
Specimen 6E Tbx2/3cDKO E18.5: embryonic day 18.5; Tbx2tm2.2Vmc/Tbx2tm2.2Vmc, Tbx3tm3.2Moon/Tbx3tm3.2Moon, Tbx18tm4(cre)Akis/Tbx18+, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: ureter Present 6E Tbx2/3cDKO E18.5 Shisa2 Expression was further augmented at E18.5 compared to E14.5.
Specimen S13 control: embryonic day 14.5; Tbx2tm2.2Vmc/?, Tbx3tm3.2Moon/?, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Structure Level Pattern Image Note
TS22: ureteral mesenchyme Present Regionally restricted S13_control Shisa2 Expression was detected in the inner region of the ureteric mesenchyme.
Specimen S13 Tbx18cre/+;Tbx2fl/fl;Tbx3fl/fl: embryonic day 14.5; Tbx2tm2.2Vmc/Tbx2tm2.2Vmc, Tbx3tm3.2Moon/Tbx3tm3.2Moon, Tbx18tm4(cre)Akis/Tbx18+, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: ureteral mesenchyme Present S13_Tbx18cre/+;Tbx2fl/fl;Tbx3fl/fl Shisa2 Expression was upregulated at E14.5 in the conditional mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
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