About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:272619 Aydogdu N, et al., TBX2 and TBX3 act downstream of canonical WNT signaling in patterning and differentiation of the mouse ureteric mesenchyme. Development. 2018 Nov 26;145(23):dev171827
Assay type: RNA in situ
MGI Accession ID: MGI:6385549
Gene symbol: Fbln2
Gene name: fibulin 2
Probe: Fbln2 probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2C control: embryonic day 18.5; Tbx2tm2.2Vmc/?, Tbx3tm3.2Moon/?, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Structure Level Pattern Image Note
TS26: adventitia of ureter Present Regionally restricted 2C control Fbln2 Expression was detected in the outer adventitial layer.
Specimen 2C Tbx18cre/+;Tbx2fl/fl;Tbx3fl/fl: embryonic day 18.5; Tbx2tm2.2Vmc/Tbx2tm2.2Vmc, Tbx3tm3.2Moon/Tbx3tm3.2Moon, Tbx18tm4(cre)Akis/Tbx18+, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: ureter Strong Regionally restricted 2C Tbx18cre/+;Tbx2fl/fl;Tbx3fl/fl Fbln2 Expression was strongly expanded to the inner mesenchymal region in the conditional mutant.
Specimen 4C control E14.5: embryonic day 14.5; Tbx2tm2.2Vmc/?, Tbx3tm3.2Moon/?, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Structure Level Pattern Image Note
TS22: ureteral mesenchyme Present Uniform 4C control E14.5 Fabln2
Specimen 4C Tbx18cre/+;Tbx2fl/fl;Tbx3fl/fl E14.5: embryonic day 14.5; Tbx2tm2.2Vmc/Tbx2tm2.2Vmc, Tbx3tm3.2Moon/Tbx3tm3.2Moon, Tbx18tm4(cre)Akis/Tbx18+, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: ureteral mesenchyme Present Uniform 4C Tbx18cre/+;Tbx2fl/fl;Tbx3fl/fl E14.5 Fbln2 Expression was found throughout the mutant ureteric mesenchyme.
Specimen 4C control E15.5: embryonic day 15.5; Tbx2tm2.2Vmc/?, Tbx3tm3.2Moon/?, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Structure Level Pattern Image Note
TS23: ureteral mesenchyme Present Uniform 4C control E15.5 Fabln2
Specimen 4C Tbx18cre/+;Tbx2fl/fl;Tbx3fl/fl E15.5: embryonic day 15.5; Tbx2tm2.2Vmc/Tbx2tm2.2Vmc, Tbx3tm3.2Moon/Tbx3tm3.2Moon, Tbx18tm4(cre)Akis/Tbx18+, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: ureteral mesenchyme Present Uniform 4C Tbx18cre/+;Tbx2fl/fl;Tbx3fl/fl E15.5 Fbln2 Expression was found throughout the mutant ureteric mesenchyme.
Specimen 4C control E16.5: embryonic day 16.5; Tbx2tm2.2Vmc/?, Tbx3tm3.2Moon/?, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Structure Level Pattern Image Note
TS24: ureteral mesenchyme Present Non-Uniform 4C control E16.5 Fabln2 Expression was downregulated in the inner layer.
Specimen 4C Tbx18cre/+;Tbx2fl/fl;Tbx3fl/fl E16.5: embryonic day 16.5; Tbx2tm2.2Vmc/Tbx2tm2.2Vmc, Tbx3tm3.2Moon/Tbx3tm3.2Moon, Tbx18tm4(cre)Akis/Tbx18+, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: ureteral mesenchyme Present Uniform 4C Tbx18cre/+;Tbx2fl/fl;Tbx3fl/fl E16.5 Fbln2 Expression was found throughout the mutant ureteric mesenchyme.
Specimen S4C control: embryonic day 18.5; Tbx2tm2.2Vmc/?, Tbx3tm3.2Moon/?, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Structure Level Pattern Image Note
TS26: adventitia of ureter Present Regionally restricted S4C control Fbln2 Expression was detected in the outer adventitial layer.
Specimen S4C Tbx18cre/+;Tbx2fl/fl: embryonic day 18.5; Tbx2tm2.2Vmc/Tbx2tm2.2Vmc, Tbx18tm4(cre)Akis/Tbx18+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: adventitia of ureter Present Regionally restricted S4C Tbx18cre/+;Tbx2fl/fl Fbln2 Expression was detected in the outer adventitial layer, as in control.
Specimen S4C Tbx18cre/+;Tbx3fl/fl: embryonic day 18.5; Tbx3tm3.2Moon/Tbx3tm3.2Moon, Tbx18tm4(cre)Akis/Tbx18+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: adventitia of ureter Present Regionally restricted S4C Tbx18cre/+;Tbx3fl/fl Fbln2 Expression was detected in the outer adventitial layer, as in control.
Specimen S4C Tbx18cre/+;Tbx2fl/+;Tbx3fl/+: embryonic day 18.5; Tbx2tm2.2Vmc/Tbx2+, Tbx3tm3.2Moon/Tbx3+, Tbx18tm4(cre)Akis/Tbx18+, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: adventitia of ureter Present Regionally restricted S4C Tbx18cre/+;Tbx2fl/+;Tbx3fl/+ Fbln2 Expression was detected in the outer adventitial layer, as in control.
Specimen S4C Tbx18cre/+;Tbx2fl/fl;Tbx3fl/+: embryonic day 18.5; Tbx2tm2.2Vmc/Tbx2tm2.2Vmc, Tbx3tm3.2Moon/Tbx3+, Tbx18tm4(cre)Akis/Tbx18+, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: adventitia of ureter Present Regionally restricted S4C Tbx18cre/+;Tbx2fl/fl;Tbx3fl/+ Fbln2 Expression was detected in the outer adventitial layer, as in control.
Specimen S4C Tbx18cre/+;Tbx2fl/+;Tbx3fl/fl: embryonic day 18.5; Tbx2tm2.2Vmc/Tbx2+, Tbx3tm3.2Moon/Tbx3tm3.2Moon, Tbx18tm4(cre)Akis/Tbx18+, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: adventitia of ureter Present Regionally restricted S4C Tbx18cre/+;Tbx2fl/+;Tbx3fl/fl Fbln2 Expression was detected in the outer adventitial layer, as in control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory