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Gene Expression Data
Assay Details
Assay
Reference: J:135407 Liao J, et al., Identification of downstream genetic pathways of Tbx1 in the second heart field. Dev Biol. 2008 Apr 15;316(2):524-37
Assay type: RNA in situ
MGI Accession ID: MGI:6385057
Gene symbol: Tbx5
Gene name: T-box 5
Probe: Tbx5 cDNA5
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2I: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: secondary heart field Trace 2I Very weak expression in second heart field (SHF).
Specimen 2J: embryonic day 9.0; Tbx1tm2.2Bem/Tbx1tm2.2Bem (more )
Structure Level Pattern Image Note
TS14: secondary heart field Present Regionally restricted 2J Authors report ectopic expression in caudal second heart field (SHF).
Specimen E9.5 +/+ not shown: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: secondary heart field Trace Very weak expression in second heart field (SHF).
Specimen E9.5 -/- not shown: embryonic day 9.5; Tbx1tm2.2Bem/Tbx1tm2.2Bem (more )
Structure Level Pattern Image Note
TS15: secondary heart field Present Regionally restricted Authors report ectopic expression in caudal second heart field (SHF).
Specimen 4G: embryonic day 9.0; Tbx1tm2.1Bem/Tbx1+, Tg(T-cre)1Lwd/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS14: secondary heart field Trace 4G Very weak expression in second heart field (SHF).
Specimen 4H: embryonic day 9.0; Tbx1tm2.1Bem/Tbx1tm2.2Bem, Tg(T-cre)1Lwd/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS14: secondary heart field Present Regionally restricted 4H Authors report same changes in expression as in Tbx1-/- embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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