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Gene Expression Data
Assay Details
Assay
Reference: J:135407 Liao J, et al., Identification of downstream genetic pathways of Tbx1 in the second heart field. Dev Biol. 2008 Apr 15;316(2):524-37
Assay type: RNA in situ
MGI Accession ID: MGI:6385049
Gene symbol: Tbx1
Gene name: T-box 1
Probe: Tbx1 probe10
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1D: embryonic day 8.75 (more )
Structure Level Pattern Image Note
TS13: branchial arch mesenchyme Present 1D
TS13: secondary heart field Present 1D
Specimen 1G: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: branchial arch mesenchyme Present 1G
TS14: secondary heart field Present 1G
Specimen 2B: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: branchial arch mesenchyme Present 2B
TS14: secondary heart field Present 2B
Specimen S3B: embryonic day 9.5; Tbx1tm2.1Bem/Tbx1+, Tg(T-cre)1Lwd/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: branchial arch endoderm Present S3B
TS15: branchial arch mesenchyme Present S3B
TS15: secondary heart field Present S3B
Specimen S3C: embryonic day 9.5; Tbx1tm2.1Bem/Tbx1tm2.2Bem, Tg(T-cre)1Lwd/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: branchial arch endoderm Present S3C Authors report normal expression in pharyngeal endoderm.
TS15: branchial arch mesenchyme Weak Regionally restricted S3C Expression reduced in mesodermal tissues but not eliminated.
TS15: secondary heart field Weak Regionally restricted S3C Expression reduced in mesodermal tissues but not eliminated.
Specimen Tbx1flox/+;T-Cre E10.5 not shown: embryonic day 10.5; Tbx1tm2.1Bem/Tbx1+, Tg(T-cre)1Lwd/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: branchial arch endoderm Present
TS17: branchial arch mesenchyme Present
Specimen Tbx1flox/-;T-Cre E10.5 not shown: embryonic day 10.5; Tbx1tm2.1Bem/Tbx1tm2.2Bem, Tg(T-cre)1Lwd/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: branchial arch endoderm Present Authors report normal expression in pharyngeal endoderm.
TS17: branchial arch mesenchyme Weak Regionally restricted Expression reduced in mesodermal tissues but not eliminated.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory