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Gene Expression Data
Assay Details
Assay
Reference: J:281434 Sato Y, et al., Comparative gene expression analysis of the engulfment and cell motility (ELMO) protein family in the mouse brain. Gene Expr Patterns. 2019 Sep 12;34:119070
Assay type: RNA in situ
MGI Accession ID: MGI:6384839
Gene symbol: Elmo3
Gene name: engulfment and cell motility 3
Probe: Elmo3 probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2A Elmo3 B6: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: cerebral cortex Strong 2A Elmo3 B6
TS25: inferior colliculus Moderate 2A Elmo3 B6
TS25: main olfactory bulb Moderate 2A Elmo3 B6
TS25: pons Moderate 2A Elmo3 B6
TS25: telencephalon ventricular layer Present Regionally restricted 2A Elmo3 B6 Expression in ventricular zone surrounding lateral ventricles.
Specimen 2A Elmo3 rl: embryonic day 17.0; Relnrl/Relnrl (more )
Structure Level Pattern Image Note
TS25: brain Present Regionally restricted 2A Elmo3 rl Authors report overall expression not severely affect by the mutation.
TS25: cerebral cortex Present Regionally restricted 2A Elmo3 rl Authors report layer-dependent expression seemed affected at E17.
Specimen 3A Elmo3: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: hippocampus Strong 3A Elmo3
Specimen 3B Elmo3 (upper): postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: brain Ambiguous 3B Elmo3 (upper)
Specimen 3B Elmo3 (middle): postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: lateral ventricle ependyma Present 3B Elmo3 (middle) Expression in ventricular zone surrounding lateral ventricles.
TS28: piriform cortex Strong 3B Elmo3 (middle)
Specimen 3B Elmo3 (lower): postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: brain Ambiguous 3B Elmo3 (lower)
Specimen 4A Elmo3 WT: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: cerebellum Present 4A Elmo3 WT
Specimen 4A Elmo3 rl: postnatal day 21; Relnrl/Relnrl (more )
Structure Level Pattern Image Note
TS28: brain Ambiguous 4A Elmo3 rl
Specimen 5A Elmo3 (1st row): postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: lateral ventricle ependyma Present Regionally restricted 5A Elmo3 (1st row) Expression in ventricular zone surrounding lateral ventricles.
Specimen 5A Elmo3 (2nd row): postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: brain Present 5A Elmo3 (2nd row)
Specimen 5A Elmo3 (3rd row): postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: amygdala Present 5A Elmo3 (3rd row)
Specimen 5A Elmo3 (4th row): postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: hippocampus Strong 5A Elmo3 (4th row)
TS28: medial habenular nucleus Present 5A Elmo3 (4th row)
TS28: arcuate nucleus Present 5A Elmo3 (4th row)
Specimen 5B Elmo3: postnatal day 21; Relnrl/Relnrl (more )
Structure Level Pattern Image Note
TS28: brain Present Regionally restricted 5B Elmo3 Authors report regional expression patterns roughly similar to those in B6 mouse brains.
Specimen 6A Elmo1 + Elmo3: embryonic day 17.0 (more )
Note: Double labeled: blue - Elmo3; magenta - Elmo1 (assay MGI:6384837).
Structure Level Pattern Image Note
TS25: cerebral cortex Present 6A Elmo1 Elmo3
Specimen 7A Elmo3: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: hippocampus Strong 7A Elmo3
Specimen 7B Elmo3 B6: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: hippocampus Weak 7B Elmo3 B6 Expression decreased at P21.
Specimen 7B Elmo3 rl: postnatal day 21; Relnrl/Relnrl (more )
Structure Level Pattern Image Note
TS28: hippocampus Ambiguous 7B Elmo3 rl In hippocampus, expression almost indistinguishable between reeler and B6 mice.
Specimen 7C Elmo3 B6: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: hippocampus Weak 7C Elmo3 B6 Expression decreased at P21.
Specimen 7C Elmo3 rl: postnatal day 21; Relnrl/Relnrl (more )
Structure Level Pattern Image Note
TS28: hippocampus Ambiguous 7C Elmo3 rl In hippocampus, expression almost indistinguishable between reeler and B6 mice.
Specimen 9A Elmo3 P7: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cerebellum Present Regionally restricted 9A Elmo3 P7
Specimen 9A Elmo3 P21: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: cerebellum Present Regionally restricted 9A Elmo3 P21
Specimen 9B Elmo3: postnatal day 21; Relnrl/Relnrl (more )
Structure Level Pattern Image Note
TS28: cerebellum Present Regionally restricted 9B Elmo3
Specimen 10A Elmo3 P7: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cerebellum Present 10A Elmo3 P7
Specimen 10A Elmo3 P21: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Ambiguous 10A Elmo3 P21
Specimen 11 Elmo3 AS P7: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cerebellum Present 11Elmo3 AS P7
Specimen 11 Elmo3 AS P21: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: cerebellum Present 11Elmo3 AS P21
Specimen Elmo3 E17 not shown: embryonic day 17.0 (more )
Note: Data presented in Table 1.
Structure Level Pattern Image Note
TS25: neocortex Strong
TS25: inferior colliculus Present
TS25: corpus striatum Weak
TS25: hippocampus marginal layer Weak
TS25: main olfactory bulb Weak
TS25: medulla oblongata Weak
TS25: pons Weak
TS25: rhombic lip Weak
TS25: superior colliculus Weak
TS25: telencephalon ventricular layer Weak
TS25: thalamus Weak
Specimen Elmo3 P21 not shown: postnatal day 21 (more )
Note: Data presented in Table 1.
Structure Level Pattern Image Note
TS28: taenia tecta Present Regionally restricted Expression in dorsal part.
TS28: olfactory tract Present Regionally restricted Expression in lateral olfactory tract.
TS28: brain ventricle Present
TS28: cerebellum Present
TS28: dentate gyrus Present
TS28: lateral ventricle Present
TS28: lateral ventricle ependyma Present
TS28: medial habenular nucleus Present
TS28: piriform cortex Present
TS28: accumbens nucleus Weak
TS28: anterior olfactory nucleus Weak
TS28: arcuate nucleus Weak
TS28: auditory cortex Weak
TS28: basolateral amygdaloid nucleus Weak
TS28: caudate-putamen Weak
TS28: central amygdaloid nucleus Weak
TS28: cerebellum granule cell layer Weak
TS28: cerebellum internal granule cell layer Weak
TS28: cingulate cortex Weak
TS28: corpus striatum Weak
TS28: cortical amygdaloid nucleus Weak
TS28: cortical layer II Weak
TS28: cortical layer III Weak
TS28: cortical layer IV Weak
TS28: cortical layer V Weak
TS28: cortical layer VI Weak
TS28: ectorhinal area Weak
TS28: endopiriform nucleus Weak
TS28: entorhinal cortex Weak
TS28: globus pallidus Weak
TS28: hippocampus CA1 Weak
TS28: hippocampus CA3 Weak
TS28: inferior colliculus Weak
TS28: lateral amygdaloid nucleus Weak
TS28: main olfactory bulb Weak
TS28: mammillary body Weak
TS28: medial amygdaloid nucleus Weak
TS28: medulla oblongata Weak
TS28: midbrain Weak
TS28: neocortex Weak
TS28: olfactory tubercle Weak
TS28: paraflocculus Weak
TS28: perirhinal cortex Weak
TS28: pons Weak
TS28: primary motor cortex Weak
TS28: primary somatosensory cortex Weak
TS28: superior colliculus Weak
TS28: temporal cortex association area Weak
TS28: thalamus Weak
TS28: vestibular nucleus Weak
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory