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Gene Expression Data
Assay Details
Assay
Reference: J:272586 Suzuki T, et al., Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes. Development. 2019 Feb 15;146(4):dev168146
Assay type: Western blot
MGI Accession ID: MGI:6382914
Gene symbol: Cnot3
Gene name: CCR4-NOT transcription complex, subunit 3
Antibody: Anti-Cnot3
Assay notes: The following genotypes could have been used as control samples: (flox/+), (flox/flox), Alb-cre;(+/+) or Alb-cre;(flox/+).
Results
Image: 1C Cnot3 ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified (a) Genetic BackgroundMutant Allele(s)Sex Note
Ctrl E16.5 E16.5 TS24: liver Present involves: 129P2/OlaHsd Not Specified
KO E16.5 E16.5 TS24: liver Present involves: 129P2/OlaHsd * C57BL/6 * DBA Cnot3tm1.2Tya/Cnot3tm1.2Tya, Speer6-ps1Tg(Alb-cre)21Mgn/0Not Specified Conditional mutant.
Ctrl d0 P0 TS27: liver Present involves: 129P2/OlaHsd Not Specified
KO d0 P0 TS27: liver Present involves: 129P2/OlaHsd * C57BL/6 * DBA Cnot3tm1.2Tya/Cnot3tm1.2Tya, Speer6-ps1Tg(Alb-cre)21Mgn/0Not Specified Conditional mutant.
Ctrl d3 P0 TS27: liver Present involves: 129P2/OlaHsd Not Specified
KO d3 P3 TS27: liver Present involves: 129P2/OlaHsd * C57BL/6 * DBA Cnot3tm1.2Tya/Cnot3tm1.2Tya, Speer6-ps1Tg(Alb-cre)21Mgn/0Not Specified Conditional mutant.
Ctrl 1w P w 1 TS28: liver Present involves: 129P2/OlaHsd Not Specified
KO 1w P w 1 TS28: liver Present involves: 129P2/OlaHsd * C57BL/6 * DBA Cnot3tm1.2Tya/Cnot3tm1.2Tya, Speer6-ps1Tg(Alb-cre)21Mgn/0Not Specified Conditional mutant.
Ctrl 4w P w 4 TS28: liver Present involves: 129P2/OlaHsd Not Specified
KO 4w P w 4 TS28: liver Present involves: 129P2/OlaHsd * C57BL/6 * DBA Cnot3tm1.2Tya/Cnot3tm1.2Tya, Speer6-ps1Tg(Alb-cre)21Mgn/0Not Specified Conditional mutant.
Notes:
(a) Expression decreased by about half at E16.5 and was largely downregulated at d3 and later in the conditional mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/09/2024
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