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Gene Expression Data
Assay Details
Assay
Reference: J:280829 Chen Y, et al., The depletion of MARVELD1 leads to murine placenta accreta via integrin beta4-dependent trophoblast cell invasion. J Cell Physiol. 2018 Mar;233(3):2257-2269
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6382095
Gene symbol: Krt18
Gene name: keratin 18
Antibody: anti-cytokeratin 18 (ab668)
Detection system: Biotinylated secondary antibody/[Strept]avidin
Results
Specimen 3b: embryonic day 18.5; Marveld1tm1.2Liy/Marveld1tm1.2Liy, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: trophectoderm Present 3b The placenta in this mutant has abnormal architecture and trophoblast cell over-invasion.
TS28: placenta Present 3b The placenta in this mutant has abnormal architecture and trophoblast cell over-invasion.
Specimen 3e +/+: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: trophectoderm Present 3e MARVELD+/+
TS28: placenta Present 3e MARVELD+/+
Specimen 3e -/-: embryonic day 18.5; Marveld1tm1.2Liy/Marveld1tm1.2Liy, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: trophectoderm Present 3e MARVELD-/- The placenta in this mutant has abnormal architecture and 3.83 times trophoblast cell over-invasion.
TS28: placenta Present 3e MARVELD-/- The placenta in this mutant has abnormal architecture and 3.83 times trophoblast cell over-invasion.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory