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Gene Expression Data
Assay Details
Assay
Reference: J:279375 Fritz KR, et al., Cdc42 activation by endothelin regulates neural crest cell migration in the cardiac outflow tract. Dev Dyn. 2019 Sep;248(9):795-812
Assay type: RNA in situ
MGI Accession ID: MGI:6379663
Gene symbol: Clvs1
Gene name: clavesin 1
Probe: Clavesin1 probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 10 Clavesin 1 E9.5 WT (upper): embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: embryo Present 10_Clavesin 1 E9.5 WT (upper)

Specimen 10 Clavesin 1 E9.5 -/- (upper): embryonic day 9.5; Ednratm1Ywa/Ednratm1Ywa (more )
Structure Level Pattern Image Note
TS15: embryo Present 10_Clavesin 1 E9.5 -/- (upper) Authors report no significant difference compared with wild-type whole embryos.

Specimen 10 Clavesin 1 E9.5 WT (lower): embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: heart Present Regionally restricted 10_Clavesin 1 E9.5 WT (lower)

Specimen 10 Clavesin 1 E9.5 -/- (lower): embryonic day 9.5; Ednratm1Ywa/Ednratm1Ywa (more )
Structure Level Pattern Image Note
TS15: bulbus cordis Weak 10_Clavesin 1 E9.5 -/- (lower) Expression significantly weaker in bulbus cordis than in wild-type heart.

Specimen 10 Clavesin 1 E10.5 WT: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: embryo Present 10_Clavesin 1 E10.5 WT

Specimen 10 Clavesin 1 E10.5 -/-: embryonic day 10.5; Ednratm1Ywa/Ednratm1Ywa (more )
Structure Level Pattern Image Note
TS17: mesenchyme derived from neural crest Weak 10_Clavesin 1 E10.5 -/- Authors report dramatic decrease in expression in neural crest cells.
TS17: limb bud Present 10_Clavesin 1 E10.5 -/-


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory