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Gene Expression Data
Assay Details
Assay
Reference: J:126341 Nam JS, et al., Mouse R-spondin2 is required for apical ectodermal ridge maintenance in the hindlimb. Dev Biol. 2007 Nov 1;311(1):124-35
Assay type: RNA in situ
MGI Accession ID: MGI:6377622
Gene symbol: Wnt3
Gene name: wingless-type MMTV integration site family, member 3
Probe: Wnt3 probe10
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 6R: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindlimb bud ectoderm Present Widespread 6R Expression in limb surface ectoderm, including the apical ectodermal ridge.

Specimen 6S: embryonic day 11.5; Rspo2tm1Nuv/Rspo2+ (more )
Structure Level Pattern Image Note
TS19: hindlimb bud ectoderm Present Widespread 6S Expression in limb surface ectoderm, including the apical ectodermal ridge.

Specimen 6T: embryonic day 11.5; Rspo2tm1Nuv/Rspo2tm1Nuv (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Trace 6T Reduced or abolished expression in apical ectodermal ridge compared to littermate controls,
TS19: hindlimb bud ectoderm Present Regionally restricted 6T No difference in surface ectoderm exopression outside apical ectodermal ridge.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory