Nkx2-2 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:178421 Dowdle WE, et al., Disruption of a ciliary B9 protein complex causes Meckel syndrome. Am J Hum Genet. 2011 Jul 15;89(1):94-110
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6370140
Gene symbol:	Nkx2-2
Gene name:	NK2 homeobox 2

Antibody:	anti-Nkx2.2
Detection system:	Alexa Fluor 488

Results

Specimen 3B +/+: embryonic day 9.5 (more

)
Note: Triple labeled: green - Nkx2-2; red - Pax6 (assay MGI:6370138); blue - DAPI.

Structure	Level	Pattern	Image	Note
TS15: neural tube	Present	Regionally restricted	3B +/+	Expression in V3 interneuron precursors.

Specimen 3B -/-: embryonic day 9.5; B9d1^{tm1d(EUCOMM)Wtsi}/B9d1^{tm1d(EUCOMM)Wtsi} (more

)
Note: Triple labeled: green - Nkx2-2; red - Pax6 (assay MGI:6370138); blue - DAPI.

Structure	Level	Pattern	Image	Note
TS15: neural tube	Weak	Regionally restricted	3B -/-	Expression is reduced.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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