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Gene Expression Data
Assay Details
Assay
Reference: J:178421 Dowdle WE, et al., Disruption of a ciliary B9 protein complex causes Meckel syndrome. Am J Hum Genet. 2011 Jul 15;89(1):94-110
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6370138
Gene symbol: Pax6
Gene name: paired box 6
Antibody: anti-Pax6
Results
Specimen 3A +/+: embryonic day 9.5 (more )
Note: Triple labeled: red - Pax6; green - Foxa2 (assay MGI:6370139); blue - DAPI.
Structure Level Pattern Image Note
TS15: neural tube Present Regionally restricted 3A +/+ Expression restricted to dorsal neural tube.
Specimen 3A -/-: embryonic day 9.5; B9d1tm1d(EUCOMM)Wtsi/B9d1tm1d(EUCOMM)Wtsi (more )
Note: Triple labeled: red - Pax6; green - Foxa2 (assay MGI:6370139); blue - DAPI.
Structure Level Pattern Image Note
TS15: neural tube Present Regionally restricted 3A -/- Expression is ventrally expanded.
Specimen 3B +/+: embryonic day 9.5 (more )
Note: Triple labeled: red - Pax6; green - Nkx2-2 (assay MGI:6370140); blue - DAPI.
Structure Level Pattern Image Note
TS15: neural tube Present Regionally restricted 3B +/+ Expression restricted to dorsal neural tube.
Specimen 3B -/-: embryonic day 9.5; B9d1tm1d(EUCOMM)Wtsi/B9d1tm1d(EUCOMM)Wtsi (more )
Note: Triple labeled: red - Pax6; green - Nkx2-2 (assay MGI:6370140); blue - DAPI.
Structure Level Pattern Image Note
TS15: neural tube Present Regionally restricted 3B -/- Expression is ventrally expanded.
Specimen 3C +/+: embryonic day 9.5 (more )
Note: Triple labeled: red - Pax6; green - Isl1 (assay MGI:6370141) and Isl2 (assay MGI:6370146); blue - DAPI.
Structure Level Pattern Image Note
TS15: neural tube Present Regionally restricted 3C +/+ Expression restricted to dorsal neural tube.
Specimen 3C -/-: embryonic day 9.5; B9d1tm1d(EUCOMM)Wtsi/B9d1tm1d(EUCOMM)Wtsi (more )
Note: Triple labeled: red - Pax6; green - Isl1 (assay MGI:6370141) and Isl2 (assay MGI:6370146); blue - DAPI.
Structure Level Pattern Image Note
TS15: neural tube Present Regionally restricted 3C -/- Expression is ventrally expanded.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/06/2026
MGI 6.24 		The Jackson Laboratory