Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Foxg1tm1.2Fsh
Name:	forkhead box G1; targeted mutation 1.2, Gordon Fishell
MGI ID:	MGI:6368632
Synonyms:	FoxG1-Flpe
Gene:	Foxg1  Location: Chr12:49429666-49433650 bp, + strand  Genetic Position: Chr12, 21.78 cM
Alliance:	Foxg1tm1.2Fsh page

Germline Transmission:	Earliest citation of germline transmission: J:188355
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Recombinase) Mutation:    Insertion   Foxg1tm1.2Fsh expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Foxg1 (MGI:1347464)   Mutation details: LoxP sites were inserted to flank the Foxg1 coding sequence. In addition, a Flpe gene was inserted 3' of the downstream loxP site, into the 3'end of the endogenous gene. An adjacent frt-flanked neomycin selection cassette was removed via Flp-mediated recombination. Cre-mediated recombination removed the Foxg1 coding sequences, leaving Flpe which is expressed from this locus. (J:188355)

Activity:	Tissue activity of this recombinase allele
Driver:	Foxg1 (mouse) Summary of all recombinase alleles driven by Foxg1. Alliance mouse Foxg1 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxg1 Mutation:	28 strains or lines available

Original:	J:188355 Miyoshi G, et al., Dynamic FoxG1 expression coordinates the integration of multipolar pyramidal neuron precursors into the cortical plate. Neuron. 2012 Jun 21;74(6):1045-58
All:	1 reference(s)