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Gene Expression Data
Assay Details
Assay
Reference: J:117138 Kimura T, et al., The stabilization of beta-catenin leads to impaired primordial germ cell development via aberrant cell cycle progression. Dev Biol. 2006 Dec 15;300(2):545-53
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6363485
Gene symbol: Dppa3
Gene name: developmental pluripotency-associated 3
Antibody: anti-PGC7
Results
Specimen 3B Control: embryonic day 13.5 (more )
Note: Double labeled: green - Pgc7 (Dppa3); red - beta-catenin (Ctnnb1 assay MGI:6363496).
Structure Level Pattern Image Note
TS21: primordial germ cell of gonad Present 3B PGC7 beta-catenin Control
Specimen 3B Pten KO: embryonic day 13.5; Ptentm1Mak/Ptentm1Mak (more )
Note: Double labeled: green - Pgc7 (Dppa3); red - beta-catenin (Ctnnb1 assay MGI:6363496).
Structure Level Pattern Image Note
TS21: primordial germ cell of gonad Present 3B PGC7 beta-catenin Pten KO
Specimen 4A E11.5 Control PGC7: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: primordial germ cell of gonad Present 4A E11.5 Control
Specimen 4A E11.5 Mutant PGC7: embryonic day 11.5; Alpltm1(cre)Nagy/Alpl+, Ctnnb1tm1Mmt/Ctnnb1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: primordial germ cell of gonad Present 4A E11.5 Mutant (left)
Specimen 4B E11.5 Control PGC7: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: primordial germ cell of gonad Present 4B E11.5 Control
Specimen 4B E11.5 Mutant PGC7: embryonic day 11.5; Alpltm1(cre)Nagy/Alpl+, Ctnnb1tm1Mmt/Ctnnb1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: primordial germ cell of gonad Present 4B E11.5 Mutant (left)
Specimen 5A Control PGC7: embryonic day 12.0 (more )
Note: Double labeled: blue - Pgc7 (Dppa3); red - Lysotracker.
Structure Level Pattern Image Note
TS20: primordial germ cell of gonad Present 5A Control (upper)
Specimen 5A Mutant PGC7: embryonic day 12.0; Alpltm1(cre)Nagy/Alpl+, Ctnnb1tm1Mmt/Ctnnb1+ (more )
Note: Conditional mutant. Double labeled: blue - Pgc7 (Dppa3); red - Lysotracker.
Structure Level Pattern Image Note
TS20: primordial germ cell of gonad Present 5A Mutant (upper)
Specimen 5B Control PGC7: embryonic day 12.0 (more )
Note: Double labeled: red - Pgc7 (Dppa3); green - Mki67 (assay MGI:6363480).
Structure Level Pattern Image Note
TS20: primordial germ cell of gonad Present 5B Control (lower) , 5B Control (upper)
Specimen 5B Mutant PGC7: embryonic day 12.0; Alpltm1(cre)Nagy/Alpl+, Ctnnb1tm1Mmt/Ctnnb1+ (more )
Note: Conditional mutant. Double labeled: red - Pgc7 (Dppa3); green - Mki67 (assay MGI:6363480).
Structure Level Pattern Image Note
TS20: primordial germ cell of gonad Present 5B Mutant (lower) , 5B Mutant (upper)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory