About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:117138 Kimura T, et al., The stabilization of beta-catenin leads to impaired primordial germ cell development via aberrant cell cycle progression. Dev Biol. 2006 Dec 15;300(2):545-53
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6363485
Gene symbol: Dppa3
Gene name: developmental pluripotency-associated 3
Antibody: anti-PGC7
Results
Specimen 3B Control: embryonic day 13.5 (more )
Note: Double labeled: green - Pgc7 (Dppa3); red - beta-catenin (Ctnnb1 assay MGI:6363496).
Structure Level Pattern Image Note
TS21: primordial germ cell of gonad Present 3B PGC7 beta-catenin Control
Specimen 3B Pten KO: embryonic day 13.5; Ptentm1Mak/Ptentm1Mak (more )
Note: Double labeled: green - Pgc7 (Dppa3); red - beta-catenin (Ctnnb1 assay MGI:6363496).
Structure Level Pattern Image Note
TS21: primordial germ cell of gonad Present 3B PGC7 beta-catenin Pten KO
Specimen 4A E11.5 Control PGC7: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: primordial germ cell of gonad Present 4A E11.5 Control
Specimen 4A E11.5 Mutant PGC7: embryonic day 11.5; Alpltm1(cre)Nagy/Alpl+, Ctnnb1tm1Mmt/Ctnnb1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: primordial germ cell of gonad Present 4A E11.5 Mutant (left)
Specimen 4B E11.5 Control PGC7: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: primordial germ cell of gonad Present 4B E11.5 Control
Specimen 4B E11.5 Mutant PGC7: embryonic day 11.5; Alpltm1(cre)Nagy/Alpl+, Ctnnb1tm1Mmt/Ctnnb1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: primordial germ cell of gonad Present 4B E11.5 Mutant (left)
Specimen 5A Control PGC7: embryonic day 12.0 (more )
Note: Double labeled: blue - Pgc7 (Dppa3); red - Lysotracker.
Structure Level Pattern Image Note
TS20: primordial germ cell of gonad Present 5A Control (upper)
Specimen 5A Mutant PGC7: embryonic day 12.0; Alpltm1(cre)Nagy/Alpl+, Ctnnb1tm1Mmt/Ctnnb1+ (more )
Note: Conditional mutant. Double labeled: blue - Pgc7 (Dppa3); red - Lysotracker.
Structure Level Pattern Image Note
TS20: primordial germ cell of gonad Present 5A Mutant (upper)
Specimen 5B Control PGC7: embryonic day 12.0 (more )
Note: Double labeled: red - Pgc7 (Dppa3); green - Mki67 (assay MGI:6363480).
Structure Level Pattern Image Note
TS20: primordial germ cell of gonad Present 5B Control (lower) , 5B Control (upper)
Specimen 5B Mutant PGC7: embryonic day 12.0; Alpltm1(cre)Nagy/Alpl+, Ctnnb1tm1Mmt/Ctnnb1+ (more )
Note: Conditional mutant. Double labeled: red - Pgc7 (Dppa3); green - Mki67 (assay MGI:6363480).
Structure Level Pattern Image Note
TS20: primordial germ cell of gonad Present 5B Mutant (lower) , 5B Mutant (upper)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory