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Gene Expression Data
Assay Details
Assay
Reference: J:273053 Shih HP, et al., A Gene Regulatory Network Cooperatively Controlled by Pdx1 and Sox9 Governs Lineage Allocation of Foregut Progenitor Cells. Cell Rep. 2015 Oct 13;13(2):326-36
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6361463
Gene symbol: Ptf1a
Gene name: pancreas specific transcription factor, 1a
Antibody: Anti-Ptf1a
Detection system: Secondary antibody coupled to Cy5
Results
Specimen S1CC: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: pancreas primordium Present S1CC
Specimen S1DD: embryonic day 10.5; Sox9tm1Gsr/Sox9+, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: pancreas primordium Present S1DD
Specimen S1EE: embryonic day 10.5; Pdx1tm2Cvw/Pdx1+ (more )
Structure Level Pattern Image Note
TS17: pancreas primordium Present S1EE
Specimen S1FF: embryonic day 10.5; Pdx1tm2Cvw/Pdx1+, Sox9tm1Gsr/Sox9+, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: pancreas primordium Present S1FF
Specimen S1GG: embryonic day 10.5; Sox9tm1Gsr/Sox9tm1Gsr, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: pancreas primordium Trace S1GG Expression was drastically reduced in the Sox9 mutant embryos.
Specimen S1HH: embryonic day 10.5; Pdx1tm2Cvw/Pdx1tm2Cvw (more )
Structure Level Pattern Image Note
TS17: pancreas primordium Weak S1HH Expression was diminished in the Pdx1 mutant embryos.
Specimen S1II: embryonic day 10.5; Pdx1tm2Cvw/Pdx1tm2Cvw, Sox9tm1Gsr/Sox9tm1Gsr, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: foregut Trace S1II Expression was drastically reduced in the Pdx1;Sox9 mutant embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
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