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Gene Expression Data
Assay Details
Assay
Reference: J:273053 Shih HP, et al., A Gene Regulatory Network Cooperatively Controlled by Pdx1 and Sox9 Governs Lineage Allocation of Foregut Progenitor Cells. Cell Rep. 2015 Oct 13;13(2):326-36
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6361425
Gene symbol: Pdx1
Gene name: pancreatic and duodenal homeobox 1
Reporter: lacZ
Direct Detection
Results
Specimen 3I: embryonic day 10.5; Pdx1tm2Cvw/Pdx1+ (more )
Structure Level Pattern Image Note
TS17: stomach Present Regionally restricted 3I Expression was detected in antral stomach
TS17: duodenum Present 3I
TS17: pancreas primordium dorsal bud Present 3I
TS17: pancreas primordium ventral bud Present 3I
Specimen 3J: embryonic day 12.5; Pdx1tm2Cvw/Pdx1+ (more )
Structure Level Pattern Image Note
TS20: stomach Present Regionally restricted 3J Expression was detected in antral stomach
TS20: duodenum Present 3J
TS20: pancreas Present 3J
Specimen 3K: embryonic day 10.5; Pdx1tm2Cvw/Pdx1+, Sox9tm1Gsr/Sox9+, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: stomach Present Regionally restricted 3K Expression was detected in antral stomach
TS17: duodenum Present 3K
TS17: pancreas primordium dorsal bud Present 3K
TS17: pancreas primordium ventral bud Present 3K
Specimen 3L: embryonic day 12.5; Pdx1tm2Cvw/Pdx1+, Sox9tm1Gsr/Sox9+, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: stomach Present Regionally restricted 3L Expression was detected in antral stomach
TS20: duodenum Present 3L
TS20: pancreas Present 3L
Specimen 3M: embryonic day 10.5; Pdx1tm2Cvw/Pdx1+, Sox9tm1Gsr/Sox9tm1Gsr, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: stomach Present Regionally restricted 3M Expression was detected in antral stomach
TS17: duodenum Present 3M
TS17: pancreas primordium dorsal bud Present 3M
TS17: pancreas primordium ventral bud Present 3M
Specimen 3N: embryonic day 12.5; Pdx1tm2Cvw/Pdx1+, Sox9tm1Gsr/Sox9tm1Gsr, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: stomach Present Regionally restricted 3N Expression was detected in antral stomach
TS20: duodenum Present 3N
TS20: pancreas Present 3N The ventral pancreatic bud was not discernable.
Specimen 3O: embryonic day 10.5; Pdx1tm2Cvw/Pdx1tm2Cvw (more )
Structure Level Pattern Image Note
TS17: stomach Present Regionally restricted 3O Expression was detected in antral stomach
TS17: duodenum Present 3O
TS17: pancreas primordium dorsal bud Present 3O
TS17: foregut-midgut junction Present 3O With increasing loss of Sox9 dosage on the Pdx1 null background, dorsal and ventral pancreatic buds become increasingly hypoplastic and not discernable.
Specimen 3P: embryonic day 12.5; Pdx1tm2Cvw/Pdx1tm2Cvw (more )
Structure Level Pattern Image Note
TS20: stomach Present Regionally restricted 3P Expression was detected in antral stomach
TS20: duodenum Present 3P
TS20: pancreas Present 3P With increasing loss of Sox9 dosage on the Pdx1 null background, dorsal and ventral pancreatic buds become increasingly hypoplastic and not discernable.
Specimen 3Q: embryonic day 10.5; Pdx1tm2Cvw/Pdx1tm2Cvw, Sox9tm1Gsr/Sox9+, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: stomach Present Regionally restricted 3Q Expression was detected in antral stomach
TS17: duodenum Present 3Q
TS17: pancreas primordium dorsal bud Present 3Q
TS17: foregut-midgut junction Present 3Q With increasing loss of Sox9 dosage on the Pdx1 null background, dorsal and ventral pancreatic buds become increasingly hypoplastic and not discernable.
Specimen 3R: embryonic day 12.5; Pdx1tm2Cvw/Pdx1tm2Cvw, Sox9tm1Gsr/Sox9+, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: stomach Present Regionally restricted 3R Expression was detected in antral stomach
TS20: duodenum Present 3R
TS20: pancreas Present 3R With increasing loss of Sox9 dosage on the Pdx1 null background, dorsal and ventral pancreatic buds become increasingly hypoplastic and not discernable.
Specimen 3S: embryonic day 10.5; Pdx1tm2Cvw/Pdx1tm2Cvw, Sox9tm1Gsr/Sox9tm1Gsr, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: stomach Present Regionally restricted 3S Expression was detected in antral stomach
TS17: duodenum Present 3S
TS17: foregut-midgut junction Present 3S With increasing loss of Sox9 dosage on the Pdx1 null background, dorsal and ventral pancreatic buds become increasingly hypoplastic and not discernable.
Specimen 3T: embryonic day 12.5; Pdx1tm2Cvw/Pdx1tm2Cvw, Sox9tm1Gsr/Sox9tm1Gsr, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: stomach Present Regionally restricted 3T Expression was detected in antral stomach
TS20: duodenum Present 3T
TS20: foregut-midgut junction Present 3T With increasing loss of Sox9 dosage on the Pdx1 null background, dorsal and ventral pancreatic buds become increasingly hypoplastic and not discernable.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
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