Pitx1 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:99697 Liu W, et al., Threshold-specific requirements for Bmp4 in mandibular development. Dev Biol. 2005 Jul 15;283(2):282-93
Assay type:	RNA in situ
MGI Accession ID:	MGI:6355433
Gene symbol:	Pitx1
Gene name:	paired-like homeodomain transcription factor 1

Probe:	Pitx1 probe11
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

6E ©

Specimen 6E: embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: 1st branchial arch mandibular component mesenchyme	Present	Regionally restricted	6E	Expression in proximal mesenchyme.

6F ©

Specimen 6F: embryonic day 10.5; Bmp4^tm1Jfm/Bmp4^tm1.1Jfm, Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS17: 1st branchial arch mandibular component mesenchyme	Present	Regionally restricted	6F	Authors report complete shift from proximal to distal in mutant compared with wild type.

6G ©

Specimen 6G: embryonic day 10.5; Bmp4^tm1Jfm/Bmp4^tm1.1Jfm, Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS17: 1st branchial arch mandibular component mesenchyme	Present	Regionally restricted	6G	In some embryos, shift from proximal to distal in mutant was incomplete.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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