About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:91443 Wilm B, et al., The forkhead genes, Foxc1 and Foxc2, regulate paraxial versus intermediate mesoderm cell fate. Dev Biol. 2004 Jul 1;271(1):176-89
Assay type: RNA in situ
MGI Accession ID: MGI:6342067
Gene symbol: Osr1
Gene name: odd-skipped related transcription factor 1
Probe: Osr1 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1E: embryonic day 8.0 (more )
Note: 6 somite stage embryo.
Structure Level Pattern Image Note
TS12: intermediate mesenchyme Present Regionally restricted 1E Expression in presumptive intermediate mesoderm in the posterior, and in definitive intermediate mesoderm lateral to somite anteriorly.
Specimen 1F: embryonic day 8.0; Foxc2tm1Blh/Foxc2tm1Blh (more )
Note: 6 somite stage embryo.
Structure Level Pattern Image Note
TS12: intermediate mesenchyme Present Regionally restricted 1F No change in expression in presumptive intermediate mesoderm.
TS12: embryo mesoderm Present Regionally restricted 1F Expression is medially expanded in a gene dosage-dependent manner.
Specimen 1G: embryonic day 8.0; Foxc1tm1Blh/Foxc1+, Foxc2tm1Blh/Foxc2tm1Blh (more )
Note: 6 somite stage embryo.
Structure Level Pattern Image Note
TS12: intermediate mesenchyme Present Regionally restricted 1G No change in expression in presumptive intermediate mesoderm.
TS12: embryo mesoderm Present Regionally restricted 1G Expression is medially expanded in a gene dosage-dependent manner.
Specimen 1H: embryonic day 8.0; Foxc1tm1Blh/Foxc1tm1Blh, Foxc2tm1Blh/Foxc2tm1Blh (more )
Note: 6 somite stage embryo.
Structure Level Pattern Image Note
TS12: intermediate mesenchyme Present Regionally restricted 1H No change in expression in presumptive intermediate mesoderm.
TS12: embryo mesoderm Present Regionally restricted 1H Expression is medially expanded, extending to cells abutting the neural tube.
Specimen 2G: embryonic day 8.0 (more )
Note: 6 somite stage embryo.
Structure Level Pattern Image Note
TS12: intermediate mesenchyme Strong 2G
TS12: somatopleure Strong Regionally restricted 2G Strong expression in medial aspects of somatopleure and splanchnopleure of lateral plate mesoderm at the level of somite III.
TS12: splanchnopleure Strong Regionally restricted 2G Strong expression in medial aspects of somatopleure and splanchnopleure of lateral plate mesoderm at the level of somite III.
TS12: somite Present Regionally restricted 2G Expression in the lateral part of the forming somites.
Specimen 2H: embryonic day 8.0; Foxc1tm1Blh/Foxc1+, Foxc2tm1Blh/Foxc2tm1Blh (more )
Note: 6 somite stage embryo.
Structure Level Pattern Image Note
TS12: intermediate mesenchyme Strong 2H Strong expression throughout the intermediate mesoderm.
TS12: lateral plate mesoderm Strong Regionally restricted 2H Strong expression in medial lateral plate mesoderm.
TS12: somite Present Regionally restricted 2H Strong expression in the somites adjacent to the neural tube.
Specimen 2I: embryonic day 8.0; Foxc1tm1Blh/Foxc1tm1Blh, Foxc2tm1Blh/Foxc2tm1Blh (more )
Note: 6 somite stage embryo.
Structure Level Pattern Image Note
TS12: embryo mesoderm Present Regionally restricted 2I Expression adjacent to the neural folds and in the lateral plate mesoderm.
TS12: lateral plate mesoderm Present 2I
Specimen 2J: embryonic day 8.0 (more )
Note: 6 somite stage embryo.
Structure Level Pattern Image Note
TS12: unsegmented mesenchyme Strong 2J Strong expression in unsegmented mesoderm.
Specimen 2K: embryonic day 8.0; Foxc1tm1Blh/Foxc1+, Foxc2tm1Blh/Foxc2tm1Blh (more )
Note: 6 somite stage embryo.
Structure Level Pattern Image Note
TS12: unsegmented mesenchyme Present Regionally restricted 2K Expression is not medially expanded at the level of unseqmented paraxial mesoderm.
Specimen 2L: embryonic day 8.0; Foxc1tm1Blh/Foxc1tm1Blh, Foxc2tm1Blh/Foxc2tm1Blh (more )
Note: 6 somite stage embryo.
Structure Level Pattern Image Note
TS12: intermediate mesenchyme Present 2L Expression restricted to the intermediate mesoderm and lateral plate mesoderm domain.
TS12: lateral plate mesoderm Present 2L Expression restricted to the intermediate mesoderm and lateral plate mesoderm domain.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory