Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Fcgr1tm1.1(icre)Ciphe
Name:	Fc receptor, IgG, high affinity I; targeted mutation 1.1, Centre d'ImmunoPhenomique
MGI ID:	MGI:6330739
Synonyms:	Fcgr1-cre, Fcgr1tm2Ciph
Gene:	Fcgr1  Location: Chr3:96190225-96201285 bp, - strand  Genetic Position: Chr3, 41.72 cM
Alliance:	Fcgr1tm1.1(icre)Ciphe page

Germline Transmission:	Earliest citation of germline transmission: J:274437
Parent Cell Line:	JM8.F6 (ES Cell)
Strain of Origin:	C57BL/6N

Allele Type:    Targeted (Recombinase, Reporter) Mutation:    Insertion   Fcgr1tm1.1(icre)Ciphe expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Fcgr1 (MGI:95498)   Mutation details: An IRES-iCRE-2A-TEAL-frt-neoR-frt cassette was introduced in the 3' untranslated region of the Fcgr1 gene, downstream of the stop codon by homologous recombination. Upon germline transmission, mice were then crossed to mice expressing the site-specific recombinase to delete the frt-flanked neoR cassette. (J:274437)

Activity:	Tissue activity of this recombinase allele
Driver:	Fcgr1 (mouse) Summary of all recombinase alleles driven by Fcgr1. Alliance mouse Fcgr1 gene page

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fcgr1 Mutation:	34 strains or lines available

Original:	J:274437 Scott CL, et al., The Transcription Factor ZEB2 Is Required to Maintain the Tissue-Specific Identities of Macrophages. Immunity. 2018 Aug 21;49(2):312-325.e5
All:	3 reference(s)