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Gene Expression Data
Assay Details
Assay
Reference: J:151925 Li Y, et al., Targeted deletion of Dicer disrupts lens morphogenesis, corneal epithelium stratification, and whole eye development. Dev Dyn. 2009 Sep;238(9):2388-400
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6317396
Gene symbol: Pax6
Gene name: paired box 6
Antibody: anti-Pax6 (#PRB-278P; #30130, #901301)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 6A: embryonic day 14.5; Dicer1tm1Smr/Dicer1tm1Smr (more )
Structure Level Pattern Image Note
TS22: lens epithelium Present 6A
Specimen 6B: embryonic day 14.5; Dicer1tm1Smr/Dicer1tm1Smr, Tg(Pax6-cre,GFP)1Pgr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: lens epithelium Present 6B Expression in overal fewer cells than in control lenses, but expression in remaining cells appeared similar to wild type.
Specimen 6C: embryonic day 16.5; Dicer1tm1Smr/Dicer1tm1Smr (more )
Structure Level Pattern Image Note
TS24: lens epithelium Present 6C
Specimen 6D: embryonic day 16.5; Dicer1tm1Smr/Dicer1tm1Smr, Tg(Pax6-cre,GFP)1Pgr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: lens epithelium Weak 6D Expression gradually lost between E16.5 and E18.5.
Specimen 6E: embryonic day 18.5; Dicer1tm1Smr/Dicer1tm1Smr (more )
Structure Level Pattern Image Note
TS26: lens epithelium Present 6E
TS26: cornea Present 6E
Specimen 6F: embryonic day 18.5; Dicer1tm1Smr/Dicer1tm1Smr, Tg(Pax6-cre,GFP)1Pgr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: lens epithelium Absent 6F Expression gradually lost between E16.5 and E18.5.
TS26: cornea Present 6F Authors report similar expression in corneal epithelium between DicerCN and wild type mice at E18.5.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/28/2026
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