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Gene Expression Data
Assay Details
Assay
Reference: J:264207 Rodgers HM, et al., The role of the Rx homeobox gene in retinal progenitor proliferation and cell fate specification. Mech Dev. 2018 Jun;151:18-29
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6317221
Gene symbol: Otx2
Gene name: orthodenticle homeobox 2
Antibody: Anti-Otx2
Results
Specimen 9A: embryonic day 17.5; Gt(ROSA)26Sortm2Sho/Gt(ROSA)26Sor+, Raxtm1.1Lwd/Rax+, Tg(Pax6-cre,GFP)2Pgr/0 (more )
Note: Conditional mutant. Double labeled: red - Otx2; green - Cre reporter
Structure Level Pattern Image Note
TS25: retina layer Strong Regionally restricted 9A Otx2 , 9A Merged Strong expression was detected in the photoreceptors along the length of the retina.
Specimen 9B: embryonic day 17.5; Gt(ROSA)26Sortm2Sho/Gt(ROSA)26Sor+, Raxtm1.1Lwd/Raxtm1Mjam, Tg(Pax6-cre,GFP)2Pgr/0 (more )
Note: Conditional mutant. Double labeled: red - Otx2; green - Cre reporter
Structure Level Pattern Image Note
TS25: retina layer Strong Regionally restricted 9B Otx2 , 9B Merged Strong expression was detected in the central portion of the conditional knockout retina, but decreased Otx2 labeling was noted in the distal portion of the retina in the Rx-deletion region.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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