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Gene Expression Data
Assay Details
Assay
Reference: J:264207 Rodgers HM, et al., The role of the Rx homeobox gene in retinal progenitor proliferation and cell fate specification. Mech Dev. 2018 Jun;151:18-29
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6317220
Gene symbol: Gngt2
Gene name: guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
Antibody: Anti-Gngt2
Results
Specimen S1A: embryonic day 17.5; Gt(ROSA)26Sortm2Sho/Gt(ROSA)26Sor+, Raxtm1.1Lwd/Rax+, Tg(Pax6-cre,GFP)2Pgr/0 (more )
Note: Conditional mutant. Double labeled: green - Gngt2; red - Pdc (assay MGI:6317214).
Structure Level Pattern Image Note
TS25: retina Present Regionally restricted S1A Gngt2 , S1A Merged Strong co-expression was noted with Pdc.
Specimen S1B: embryonic day 17.5; Gt(ROSA)26Sortm2Sho/Gt(ROSA)26Sor+, Raxtm1.1Lwd/Raxtm1Mjam, Tg(Pax6-cre,GFP)2Pgr/0 (more )
Note: Conditional mutant. Double labeled: green - Gngt2; red - Pdc (assay MGI:6317214).
Structure Level Pattern Image Note
TS25: retina Present Regionally restricted S1B Merged , S1B Gngt2 In the Rx conditional knockout retina, the central portion of the retina displays co-expression with Pdc, but the expression is greatly reduced in the distal portion of the retina.
Specimen S1C: postnatal day 0; Gt(ROSA)26Sortm2Sho/Gt(ROSA)26Sor+, Raxtm1.1Lwd/Rax+, Tg(Pax6-cre,GFP)2Pgr/0 (more )
Note: Conditional mutant. Double labeled: green - Gngt2; red - Pdc (assay MGI:6317214).
Structure Level Pattern Image Note
TS27: retina Present Regionally restricted S1C Merged , S1C Gngt2 Strong co-expression was noted with Pdc.
Specimen S1D: postnatal day 0; Gt(ROSA)26Sortm2Sho/Gt(ROSA)26Sor+, Raxtm1.1Lwd/Raxtm1Mjam, Tg(Pax6-cre,GFP)2Pgr/0 (more )
Note: Conditional mutant. Double labeled: green - Gngt2; red - Pdc (assay MGI:6317214).
Structure Level Pattern Image Note
TS27: retina Present Regionally restricted S1D Gngt2 , S1D Merged In the Rx conditional knockout retina, the central portion of the retina displays co-expression with Pdc, but the expression is greatly reduced in the distal portion of the retina.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
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