About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:229895 Sugiyama Y, et al., Non-essential role for cilia in coordinating precise alignment of lens fibres. Mech Dev. 2016 Feb;139:10-7
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6315340
Gene symbol: Ift88
Gene name: intraflagellar transport 88
Antibody: Anti-IFT88
Results
Specimen 2Aa: embryonic day 16.5; Ift88tm1Bky/Ift88tm1Bky (more )
Note: Double labeled: green - Ift88; purple - Ctnnb1 (assay MGI:6315342).
Structure Level Pattern Image Note
TS24: anterior lens fiber Present 2Ac' , 2Aa , 2Ac , 2Aa' Expression was found at the apical surfaces of the epithelial and fiber cells in the control lenses in a region anterior to the equator.
TS24: lens anterior epithelium Present 2Ac' , 2Aa , 2Ac , 2Aa' Expression was found at the apical surfaces of the epithelial and fiber cells in the control lenses in a region anterior to the equator.
Specimen 2Ad: embryonic day 16.5; Ift88tm1Bky/Ift88tm1Bky, Tg(Cryaa-cre)10Mlr/0 (more )
Note: Conditional mutant. Double labeled: green - Ift88; purple - Ctnnb1 (assay MGI:6315342).
Structure Level Pattern Image Note
TS24: anterior lens fiber Trace Single cells 2Af , 2Ad' , 2Af' , 2Ad The conditional knock-out lenses were mostly depleted of signal, although some remants were still detectable. Signal was detected as dots at the bases and the tips of cilia.
TS24: lens anterior epithelium Trace Single cells 2Af , 2Ad' , 2Af' , 2Ad The conditional knock-out lenses were mostly depleted of signal, although some remants were still detectable. Signal was detected as dots at the bases and the tips of cilia.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory