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Gene Expression Data
Assay Details
Assay
Reference: J:269344 Teng CS, et al., Altered bone growth dynamics prefigure craniosynostosis in a zebrafish model of Saethre-Chotzen syndrome. Elife. 2018 Oct 25;7:e37024
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6315227
Gene symbol: Grem1
Gene name: gremlin 1, DAN family BMP antagonist
Antibody: GREM1 Polyclonal Antibody (PA5-47973)
Detection system: Alexa Fluor 568
Results
Specimen 7C upper right: embryonic day 14.5 (more )
Note: Double labeled: red - Grem1; green - Sp7 (assay MGI:6315209).
Structure Level Pattern Image Note
TS22: frontal bone primordium Present 7C right upper
TS22: parietal bone primordium Present 7C right upper
Specimen 7C lower right: embryonic day 14.5; Tcf12tm3.1Zhu/Tcf12+, Twist1tm1Bhr/Twist1+ (more )
Note: Double labeled: red - Grem1; green - Sp7 (assay MGI:6315209).
Structure Level Pattern Image Note
TS22: frontal bone primordium Present 7C right lower Marked reduction in the number of positive putative progenitors at and around the developing coronal bone front.
TS22: parietal bone primordium Present 7C right lower Marked reduction in the number of positive putative progenitors at and around the developing coronal bone front.
Specimen 7D upper right: embryonic day 16.5 (more )
Note: Double labeled: red - Grem1; green - Sp7 (assay MGI:6315209).
Structure Level Pattern Image Note
TS24: parietal bone Present 7D right upper
Specimen 7D lower right: embryonic day 16.5; Tcf12tm3.1Zhu/Tcf12+, Twist1tm1Bhr/Twist1+ (more )
Note: Double labeled: red - Grem1; green - Sp7 (assay MGI:6315209).
Structure Level Pattern Image Note
TS24: parietal bone Present 7D right lower Similar as in the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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