Tcf12^tm3.1Zhu
Targeted Allele Detail

Summary

• Symbol: Tcf12^tm3.1Zhu
• Name: transcription factor 12; targeted mutation 3.1, Yuan Zhuan
• MGI ID: MGI:6315228
• Gene: Tcf12 Location: Chr9:71751534-72019611 bp, - strand Genetic Position: Chr9, 39.85 cM
• Alliance: Tcf12^tm3.1Zhu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:269344
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A floxed neo cassette was inserted into intron 18 and an additional loxP site was inserted into intron 17. Cre-mediated recombination removed the selection cassette and exon 18. (J:269344)

Expression

In Mice Carrying this Mutation:

18 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tcf12 Mutation: 75 strains or lines available

References

• Original: J:269344 Teng CS, et al., Altered bone growth dynamics prefigure craniosynostosis in a zebrafish model of Saethre-Chotzen syndrome. Elife. 2018 Oct 25;7:e37024
• All: 1 reference(s)