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Gene Expression Data
Assay Details
Assay
Reference: J:274453 Shin JO, et al., BMP4 signaling mediates Zeb family in developing mouse tooth. Histochem Cell Biol. 2012 Jun;137(6):791-800
Assay type: RNA in situ
MGI Accession ID: MGI:6314743
Gene symbol: Zeb1
Gene name: zinc finger E-box binding homeobox 1
Probe: Zeb1 cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1a: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: perichondrium Present Regionally restricted 1a Expression was detected in the lingual portion of the perichondrium of Meckel's cartilage.
TS21: cranial muscle Present Regionally restricted 1a Expression was detected in the developing mylohyoid muscle fibers on the lingual side of the Meckel's cartilage.
TS21: Meckel's cartilage Present Regionally restricted 1a Expression was detected in chondrocytes.

Specimen 1b: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: palatal shelf mesenchyme Present 1b

Specimen 1c: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: hair follicle Present Regionally restricted 1c Expression was detected in the mesenchyme of the developing hair follicle, but not in the hair germ.

Specimen 1d: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: Meckel's cartilage Strong Regionally restricted 1d Strong expression was detected in the ventrolingual and dorsobuccal sides of the Meckel's cartilage. There was no expression in the chondrocytes in Meckel's cartilage.
TS22: mylohyoid Present 1d

Specimen 1e: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: palatal shelf mesenchyme Present 1e
TS22: palatal shelf epithelium Absent 1e There was no expression in the midline epithelial seam.

Specimen 1f: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: hair follicle Strong Regionally restricted 1f In the superficial region of the hair follicle, strong expression was detected in the outer root sheath and adjacent mesenchyme. In the deep region of the hair follicle, expression was weak in the outer root sheath and stronger in the inner root sheath.

Specimen 1g: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: mylohyoid Present 1g
TS24: Meckel's cartilage Ambiguous 1g There was no expression in the chondrocytes in Meckel's cartilage.

Specimen 1h: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: palate mesenchyme Strong 1h
TS24: hard palate Absent 1h There was no expression in palatal bone region.

Specimen 1i: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: hair follicle dermal papilla Strong 1i
TS24: hair root sheath Strong 1i

Specimen 1s: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS21: tooth mesenchyme Present 1s

Specimen 1t: embryonic day 13.5 (more )
Note: Bud stage.
Structure Level Pattern Image Note
TS21: tooth mesenchyme Present 1t
TS21: tooth epithelium Absent 1t

Specimen 1u: embryonic day 14.5 (more )
Note: Cap stage.
Structure Level Pattern Image Note
TS22: dental papilla Strong 1u
TS22: dental sac Weak 1u

Specimen 1v: embryonic day 16.5 (more )
Note: Early bell stage.
Structure Level Pattern Image Note
TS24: dental papilla Present 1v Expression was more evident in the dental papilla than in the dental follicle.
TS24: dental sac Present 1v Expression was more evident in the dental papilla than in the dental follicle.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory