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Gene Expression Data
Assay Details
Assay
Reference: J:60838 Haigh JJ, et al., Conditional inactivation of VEGF-A in areas of collagen2a1 expression results in embryonic lethality in the heterozygous state. Development. 2000 Apr;127(7):1445-53
Assay type: RNA in situ
MGI Accession ID: MGI:6306881
Gene symbol: Kdr
Gene name: kinase insert domain protein receptor
Probe: flk-1 probe4
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: intersomitic blood vessel Present Regionally restricted 1C Expression in endothelium of intersomitic blood vessels.
Specimen 4H: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: intersomitic blood vessel Present Regionally restricted 4H Expression in vascular endothelium.
Specimen 4I: embryonic day 10.5; Vegfatm2Gne/Vegfa+, Tg(COL2A1-cre)1Wag/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: intersomitic blood vessel Present Regionally restricted 4I Expression in decreased number of cells. Authors report dramatic discorganization of developing endothelium which appears discontinuous with regions of vascular hemorrhaging.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory