About   Help   FAQ
flk-1 probe4 Probe Detail
Nucleotide
Probe/Clone
  • Name
    flk-1 probe4
  • Sequence Type
    cDNA
  • ID
    MGI:1320868
  • Region Covered
    extracellular and transmembrane domains
  • Vector Type
    Plasmid
  • Insert Site
    EcoRI/BamHI
  • Insert Size
    2.62kb
Source
  • Species
    mouse, laboratory
  • Age
    embryonic
  • Tissue
    embryo
Genes
Kdr kinase insert domain protein receptor
Expression
  • Assay Results
    80
Sequences
References
J:36300 Millauer B, et al., High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis. Cell. 1993 Mar 26;72(6):835-46
J:26913 Dickson MC, et al., Defective haematopoiesis and vasculogenesis in transforming growth factor-beta 1 knock out mice. Development. 1995 Jun;121(6):1845-54
J:29513 Breier G, et al., Coordinate expression of vascular endothelial growth factor receptor-1 (flt-1) and its ligand suggests a paracrine regulation of murine vascular development. Dev Dyn. 1995 Nov;204(3):228-39
J:43434 George EL, et al., Fibronectins are essential for heart and blood vessel morphogenesis but are dispensable for initial specification of precursor cells. Blood. 1997 Oct 15;90(8):3073-81
J:60838 Haigh JJ, et al., Conditional inactivation of VEGF-A in areas of collagen2a1 expression results in embryonic lethality in the heterozygous state. Development. 2000 Apr;127(7):1445-53
J:65292 Schreiber M, et al., Placental vascularisation requires the AP-1 component fra1. Development. 2000 Nov;127(22):4937-48
J:118798 Fan B, et al., Hepatocyte growth factor activator inhibitor-1 (HAI-1) is essential for the integrity of basement membranes in the developing placental labyrinth. Dev Biol. 2007 Mar 1;303(1):222-30

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/18/2025
MGI 6.24
The Jackson Laboratory