About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:196291 Ryu YK, et al., An autocrine Wnt5a-Ror signaling loop mediates sympathetic target innervation. Dev Biol. 2013 May 1;377(1):79-89
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6294269
Gene symbol: Th
Gene name: tyrosine hydroxylase
Antibody: anti-TH
Detection system: horseradish peroxidase
Results
Specimen 2D WT: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: sympathetic ganglion Present 2D WT
Specimen 2D Wnt1::Cre;Wnt5a fl/-: embryonic day 16.5; Wnt5atm1Amc/Wnt5atm1.1Krvl, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: sympathetic ganglion Present 2D Wnt::Cre;Wnt5a fl/- Authors state the general architecture of the sympathetic chain in mutant is normal, with ganglia size comparable to that of wildtype.
Specimen 3A WT: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: salivary gland Present 3A WT
Specimen 3A Wnt1::Cre;Wnt5a fl/-: embryonic day 16.5; Wnt5atm1Amc/Wnt5atm1.1Krvl, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: salivary gland Weak Regionally restricted 3A Wnt::Cre;Wnt5a fl/- Authors report reduced sympathetic arborization.
Specimen 3C WT: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: thymus Present 3C WT
Specimen 3C Wnt1::Cre;Wnt5a fl/-: embryonic day 16.5; Wnt5atm1Amc/Wnt5atm1.1Krvl, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: thymus Weak Regionally restricted 3C Wnt::Cre;Wnt5a fl/- Authors report reduced sympathetic arborization.
Specimen 3E WT: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: heart Present 3E WT
Specimen 3E Wnt1::Cre;Wnt5a fl/-: embryonic day 16.5; Wnt5atm1Amc/Wnt5atm1.1Krvl, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: heart Weak Regionally restricted 3E Wnt::Cre;Wnt5a fl/- Authors report reduced sympathetic arborization.
Specimen 3G WT: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: spleen Present 3G WT
Specimen 3G Wnt1::Cre;Wnt5a fl/-: embryonic day 16.5; Wnt5atm1Amc/Wnt5atm1.1Krvl, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: spleen Weak Regionally restricted 3G Wnt::Cre;Wnt5a fl/- Authors report reduced sympathetic arborization.
Specimen 3I WT: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: bladder Present 3I WT
Specimen 3I Wnt1::Cre;Wnt5a fl/-: embryonic day 16.5; Wnt5atm1Amc/Wnt5atm1.1Krvl, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: bladder Weak Regionally restricted 3I Wnt::Cre;Wnt5a fl/- Authors report reduced sympathetic arborization.
Specimen 4D Wnt5a fl/fl: embryonic day 16.5; Wnt5atm1.1Krvl/Wnt5atm1.1Krvl (more )
Structure Level Pattern Image Note
TS24: salivary gland Present 4D Wnt5a fl/fl
Specimen 4D TH::Cre;Wnt5a fl/fl: embryonic day 16.5; Wnt5atm1.1Krvl/Wnt5atm1.1Krvl, Tg(Th-cre)#Gsat/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: salivary gland Weak Regionally restricted 4D TH::Cre;Wnt5a fl/fl Authors report reduced sympathetic innervation of salivary gland.
Specimen 4F Wnt5a fl/fl: embryonic day 16.5; Wnt5atm1.1Krvl/Wnt5atm1.1Krvl (more )
Structure Level Pattern Image Note
TS24: heart Present 4F Wnt5a fl/fl
Specimen 4F TH::Cre;Wnt5a fl/fl: embryonic day 16.5; Wnt5atm1.1Krvl/Wnt5atm1.1Krvl, Tg(Th-cre)#Gsat/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: heart Weak Regionally restricted 4F TH::Cre;Wnt5a fl/fl Authors report reduced sympathetic innervation of heart.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory