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Gene Expression Data
Assay Details
Assay
Reference: J:196291 Ryu YK, et al., An autocrine Wnt5a-Ror signaling loop mediates sympathetic target innervation. Dev Biol. 2013 May 1;377(1):79-89
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6294268
Gene symbol: Th
Gene name: tyrosine hydroxylase
Antibody: anti-TH
Results
Specimen 2B WT: embryonic day 13.5 (more )
Note: Double labeled: red - TH; green - EdU.
Structure Level Pattern Image Note
TS21: superior cervical ganglion Present 2B WT TH , 2B WT Merge
Specimen 2B Wnt1::Cre;Wnt5a fl/-: embryonic day 13.5; Wnt5atm1Amc/Wnt5atm1.1Krvl, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. Double labeled: red - TH; green - EdU.
Structure Level Pattern Image Note
TS21: superior cervical ganglion Present 2B Wnt::Cre;Wnt5a fl/- Merge , 2B Wnt::Cre;Wnt5a fl/- TH
Specimen S3A WT: postnatal day 0.5 (more )
Note: Double labeled: red - TH; green - Casp3 (assay MGI:6294272).
Structure Level Pattern Image Note
TS27: superior cervical ganglion Present S3A WT Merge , S3A WT TH
Specimen S3A Wnt1::Cre;Wnt5a fl/-: postnatal day 0.5; Wnt5atm1Amc/Wnt5atm1.1Krvl, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. Double labeled: red - TH; green - Casp3 (assay MGI:6294272).
Structure Level Pattern Image Note
TS27: superior cervical ganglion Present S3A Wnt::Cre;Wnt5a fl/- Merge , S3A Wnt::Cre;Wnt5a fl/- TH
Specimen 4H Wnt5a fl/fl: postnatal day 7; Wnt5atm1.1Krvl/Wnt5atm1.1Krvl (more )
Structure Level Pattern Image Note
TS28: superior cervical ganglion Present 4H Wnt5a fl/fl
Specimen 4H TH::Cre;Wnt5a fl/fl: postnatal day 7; Wnt5atm1.1Krvl/Wnt5atm1.1Krvl, Tg(Th-cre)#Gsat/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: superior cervical ganglion Weak 4H TH::Cre;Wnt5a fl/fl Reduced expression in mutant compare to control mice.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory