About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:266589 Cohen-Tayar Y, et al., Pax6 regulation of Sox9 in the mouse retinal pigmented epithelium controls its timely differentiation and choroid vasculature development. Development. 2018 Aug 9;145(15):dev163691
Assay type: RT-PCR
MGI Accession ID: MGI:6293907
Gene symbol: Angptl4
Gene name: angiopoietin-like 4
Probe: Angptl4-pE, Angptl4-pF
Assay notes: Quantitative RT-PCR. Results were normalized to Tbp. Graph indicates levels of the conditional KO's relative to levels in Control.
Results
Image: 5F ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex Note
Pax6 cKO E15.5 TS23: pigmented retinal epithelium Present (a) Not Specified involves: 129S1/Sv * 129X1/SvJ * ICR Pax6tm2Pgr/Pax6tm2PgrNot Specified Conditional mutant.
Control E15.5 TS23: pigmented retinal epithelium Present Not Specified involves: 129S1/Sv * 129X1/SvJ * ICR Pax6tm2Pgr/Pax6tm2PgrNot Specified
Sox9 cKO E15.5 TS23: pigmented retinal epithelium Present Not Specified involves: 129S7/SvEvBrd * ICR Sox9tm2Crm/Sox9tm2Crm, Tg(Dct-cre)1Apdn/0Not Specified Conditional mutant.
Control E15.5 TS23: pigmented retinal epithelium Present Not Specified involves: 129S7/SvEvBrd * ICR Sox9tm2Crm/Sox9tm2CrmNot Specified
Sox9 cKO P5 TS28: pigmented retinal epithelium Weak (b) Not Specified involves: 129S7/SvEvBrd * ICR Sox9tm2Crm/Sox9tm2Crm, Tg(Dct-cre)1Apdn/0Not Specified Conditional mutant.
Control P5 TS28: pigmented retinal epithelium Present Not Specified involves: 129S7/SvEvBrd * ICR Sox9tm2Crm/Sox9tm2CrmNot Specified
Notes:
(a) Expression level was significantly increased in the Pax6 cKO compared to Control at E15.5 (fold change = 1.54).
(b) Expression level was significantly reduced in the Sox9 cKO compared to Control at P5 (fold change = 0.64).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory