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Gene Expression Data
Assay Details
Assay
Reference: J:214852 Schatz O, et al., Gene dosage of the transcription factor Fingerin (bHLHA9) affects digit development and links syndactyly to ectrodactyly. Hum Mol Genet. 2014 Oct 15;23(20):5394-401
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6286501
Gene symbol: Bhlha9
Gene name: basic helix-loop-helix family, member a9
Reporter: lacZ
Direct Detection
Results
Specimen not shown: embryonic day 9.5; Bhlha9tm1Nba/Bhlha9+ (more )
Structure Level Pattern Image Note
TS15: limb bud Present

Specimen 2 E10.5 Whole: embryonic day 10.5; Bhlha9tm1Nba/Bhlha9+ (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present 2_E10.5 Whole
TS17: hindlimb bud Present 2_E10.5 Whole

Specimen 2 E10.5 Zoom: embryonic day 10.5; Bhlha9tm1Nba/Bhlha9+ (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present Regionally restricted 2_E10.5 Zoom Expression on both dorsal and ventral sides of handplate and footplate. No expression at dorsoventral border.
TS17: hindlimb bud Present Regionally restricted 2_E10.5 Zoom Expression on both dorsal and ventral sides of handplate and footplate. No expression at dorsoventral border.

Specimen 2 E10.5 Forelimb: embryonic day 10.5; Bhlha9tm1Nba/Bhlha9+ (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present 2_E10.5 Forelimb

Specimen 2 E10.5 Hindlimb: embryonic day 10.5; Bhlha9tm1Nba/Bhlha9+ (more )
Structure Level Pattern Image Note
TS17: hindlimb bud Present 2_E10.5 Hindlimb

Specimen 2 E11.5 Whole: embryonic day 11.5; Bhlha9tm1Nba/Bhlha9+ (more )
Structure Level Pattern Image Note
TS19: footplate Present 2_E11.5 Whole
TS19: handplate Present 2_E11.5 Whole

Specimen 2 E11.5 Zoom: embryonic day 11.5; Bhlha9tm1Nba/Bhlha9+ (more )
Structure Level Pattern Image Note
TS19: footplate Present Regionally restricted 2_E11.5 Zoom Expression on both dorsal and ventral sides of handplate and footplate. No expression at dorsoventral border.
TS19: handplate Present Regionally restricted 2_E11.5 Zoom Expression on both dorsal and ventral sides of handplate and footplate. No expression at dorsoventral border.

Specimen 2 E11.5 Forelimb: embryonic day 11.5; Bhlha9tm1Nba/Bhlha9+ (more )
Structure Level Pattern Image Note
TS19: handplate Present 2_E11.5 Forelimb

Specimen 2 E11.5 Hindlimb: embryonic day 11.5; Bhlha9tm1Nba/Bhlha9+ (more )
Structure Level Pattern Image Note
TS19: footplate Present 2_E11.5 Hindlimb

Specimen 2 E12.5 Whole: embryonic day 12.5; Bhlha9tm1Nba/Bhlha9+ (more )
Structure Level Pattern Image Note
TS20: foot Present 2_E12.5 Whole
TS20: hand Present 2_E12.5 Whole

Specimen 2 E12.5 Zoom: embryonic day 12.5; Bhlha9tm1Nba/Bhlha9+ (more )
Structure Level Pattern Image Note
TS20: foot Present Regionally restricted 2_E12.5 Zoom Expression on both dorsal and ventral sides of handplate and footplate. No expression at dorsoventral border.
TS20: hand Present Regionally restricted 2_E12.5 Zoom Expression on both dorsal and ventral sides of handplate and footplate. No expression at dorsoventral border.

Specimen 2 E12.5 Forelimb: embryonic day 12.5; Bhlha9tm1Nba/Bhlha9+ (more )
Structure Level Pattern Image Note
TS20: hand Present Regionally restricted 2_E12.5 Forelimb Authors report expression distal to rays of future digits and distal to interdigital regions.

Specimen 2 E12.5 Hindlimb: embryonic day 12.5; Bhlha9tm1Nba/Bhlha9+ (more )
Structure Level Pattern Image Note
TS20: foot Present Regionally restricted 2_E12.5 Hindlimb Authors report expression distal to rays of future digits and distal to interdigital regions.

Specimen 2 E13.5 Whole: embryonic day 13.5; Bhlha9tm1Nba/Bhlha9+ (more )
Structure Level Pattern Image Note
TS21: foot Present 2_E13.5 Whole
TS21: hand Present 2_E13.5 Whole

Specimen 2 E13.5 Zoom: embryonic day 13.5; Bhlha9tm1Nba/Bhlha9+ (more )
Structure Level Pattern Image Note
TS21: foot Present Regionally restricted 2_E13.5 Zoom Expression on both dorsal and ventral sides of handplate and footplate. No expression at dorsoventral border.
TS21: hand Present Regionally restricted 2_E13.5 Zoom Expression on both dorsal and ventral sides of handplate and footplate. No expression at dorsoventral border.

Specimen 2 E13.5 Forelimb: embryonic day 13.5; Bhlha9tm1Nba/Bhlha9+ (more )
Structure Level Pattern Image Note
TS21: hand Present Regionally restricted 2_E13.5 Forelimb Authors report expression distal to rays of future digits and distal to interdigital regions.

Specimen 2 E13.5 Hindlimb: embryonic day 13.5; Bhlha9tm1Nba/Bhlha9+ (more )
Structure Level Pattern Image Note
TS21: foot Present Regionally restricted 2_E13.5 Hindlimb Authors report expression distal to rays of future digits and distal to interdigital regions.

Specimen 2 E14.5 Whole: embryonic day 14.5; Bhlha9tm1Nba/Bhlha9+ (more )
Structure Level Pattern Image Note
TS22: foot Present 2_E14.5 Whole
TS22: hand Present 2_E14.5 Whole

Specimen 2 E14.5 Zoom: embryonic day 14.5; Bhlha9tm1Nba/Bhlha9+ (more )
Structure Level Pattern Image Note
TS22: foot Present Regionally restricted 2_E14.5 Zoom Expression on both dorsal and ventral sides of handplate and footplate. No expression at dorsoventral border.
TS22: hand Present Regionally restricted 2_E14.5 Zoom Expression on both dorsal and ventral sides of handplate and footplate. No expression at dorsoventral border.

Specimen 2 E14.5 Forelimb: embryonic day 14.5; Bhlha9tm1Nba/Bhlha9+ (more )
Structure Level Pattern Image Note
TS22: hand Present Regionally restricted 2_E14.5 Forelimb Narrowed expression domain, distal to digital rays.

Specimen 2 E14.5 Hindlimb: embryonic day 14.5; Bhlha9tm1Nba/Bhlha9+ (more )
Structure Level Pattern Image Note
TS22: foot Present Regionally restricted 2_E14.5 Hindlimb Narrowed expression domain, distal to digital rays.

Specimen 2 E15.5 Whole: embryonic day 15.5; Bhlha9tm1Nba/Bhlha9+ (more )
Structure Level Pattern Image Note
TS23: foot Present 2_E15.5 Whole
TS23: hand Present 2_E15.5 Whole

Specimen 2 E15.5 Zoom: embryonic day 15.5; Bhlha9tm1Nba/Bhlha9+ (more )
Structure Level Pattern Image Note
TS23: foot Present Regionally restricted 2_E15.5 Zoom Expression on both dorsal and ventral sides of handplate and footplate. No expression at dorsoventral border.
TS23: hand Present Regionally restricted 2_E15.5 Zoom Expression on both dorsal and ventral sides of handplate and footplate. No expression at dorsoventral border.

Specimen 2 E15.5 Forelimb: embryonic day 15.5; Bhlha9tm1Nba/Bhlha9+ (more )
Structure Level Pattern Image Note
TS23: hand Present Regionally restricted 2_E15.5 Forelimb Narrowed expression domain, distal to digital rays.

Specimen 2 E15.5 Hindlimb: embryonic day 15.5; Bhlha9tm1Nba/Bhlha9+ (more )
Structure Level Pattern Image Note
TS23: foot Present Regionally restricted 2_E15.5 Hindlimb Narrowed expression domain, distal to digital rays.

Specimen 3 X-gal E14.5 left: embryonic day 14.5; Bhlha9tm1Nba/Bhlha9+ (more )
Structure Level Pattern Image Note
TS22: autopod skin Present Regionally restricted 3_E14.5 X-gal left Authors report expression in dorsal and ventral external-most layer, probably non-ridge ectoderm.

Specimen 3 X-gal E14.5 left inset: embryonic day 14.5; Bhlha9tm1Nba/Bhlha9+ (more )
Structure Level Pattern Image Note
TS22: autopod skin Present Regionally restricted 3_E14.5 X-gal left inset No expression at dorsal-ventral border.

Specimen 3 X-gal E14.5 right: embryonic day 14.5; Bhlha9tm1Nba/Bhlha9+ (more )
Structure Level Pattern Image Note
TS22: autopod skin Present Regionally restricted 3_E14.5 X-gal right Expression at outermost layer of hand and foot plates.

Specimen 3 X-gal E14.5 right inset: embryonic day 14.5; Bhlha9tm1Nba/Bhlha9+ (more )
Structure Level Pattern Image Note
TS22: autopod skin Present Regionally restricted 3_E14.5 X-gal right inset Expression confined to a layer that varies from one to a few cells thick.

Specimen 3 X-gal E12.5: embryonic day 12.5; Bhlha9tm1Nba/Bhlha9+ (more )
Structure Level Pattern Image Note
TS20: limb epithelium Present Regionally restricted 3_E12.5 X-gal Expression at outermost layer of hand and foot plates.

Specimen 3 X-gal E12.5 inset: embryonic day 12.5; Bhlha9tm1Nba/Bhlha9+ (more )
Structure Level Pattern Image Note
TS20: digit epithelium Present Regionally restricted 3_E12.5 X-gal inset Expression confined to a layer that varies from one to a few cells thick.

Specimen 3 X-gal E13.5: embryonic day 13.5; Bhlha9tm1Nba/Bhlha9+ (more )
Structure Level Pattern Image Note
TS21: autopod skin Present Regionally restricted 3_E13.5 X-gal Expression at outermost layer of hand and foot plates.

Specimen 3 X-gal E13.5 inset: embryonic day 13.5; Bhlha9tm1Nba/Bhlha9+ (more )
Structure Level Pattern Image Note
TS21: interdigital region epithelium Present Regionally restricted 3_E13.5 X-gal inset Expression confined to a layer that varies from one to a few cells thick.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory