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Gene Expression Data
Assay Details
Assay
Reference: J:266538 Backer S, et al., Trio GEF mediates RhoA activation downstream of Slit2 and coordinates telencephalic wiring. Development. 2018 Oct 2;145(19):dev153692
Assay type: RNA in situ
MGI Accession ID: MGI:6286062
Gene symbol: Trio
Gene name: triple functional domain (PTPRF interacting)
Probe: MT7
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: neocortex Present Widespread 2A Very broad expression.
TS20: telencephalon mantle layer Present Regionally restricted 2A Very broad expression in the ventral telencephalon.
TS20: lateral ganglionic eminence Present Regionally restricted 2A Expressed in the mantle layer, but low in their ventricular and subventricular zones.
TS20: medial ganglionic eminence Present Regionally restricted 2A Expressed in the mantle layer, but low in their ventricular and subventricular zones.
TS20: telencephalon subventricular zone Weak 2A
TS20: telencephalon ventricular layer Weak 2A

Specimen 2B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: neocortex Present Widespread 2B Very broad expression.
TS20: telencephalon mantle layer Present Regionally restricted 2B Very broad expression in the ventral telencephalon.
TS20: lateral ganglionic eminence Present Regionally restricted 2B Expressed in the mantle layer, but low in their ventricular and subventricular zones.
TS20: medial ganglionic eminence Present Regionally restricted 2B Expressed in the mantle layer, but low in their ventricular and subventricular zones.
TS20: telencephalon subventricular zone Weak 2B
TS20: telencephalon ventricular layer Weak 2B

Specimen 2C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cortical plate Strong 2C
TS22: thalamus Strong 2C
TS22: telencephalon Strong Regionally restricted 2C Expressed in the ventral part.
TS22: corpus striatum Present 2C
TS22: globus pallidus Present 2C
TS22: lateral ganglionic eminence Present 2C
TS22: medial ganglionic eminence Present 2C

Specimen 2D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: caudal ganglionic eminence Present 2D
TS22: neocortex Present 2D
TS22: thalamus Present 2D

Specimen 2E: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: corpus striatum Present 2E
TS27: neocortex Present 2E
TS27: subiculum Present 2E
TS27: hippocampus Present Regionally restricted 2E Expressed in the cingular anterior and infralimbic cortex.
TS27: presubiculum Present Regionally restricted 2E Expressed in the dorsolateral part.

Specimen 2F: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: neocortex Present 2F
TS27: subiculum Present 2F
TS27: thalamus Present 2F
TS27: hippocampus Present Regionally restricted 2F Expressed in the cingular anterior and infralimbic cortex.
TS27: presubiculum Present Regionally restricted 2F Expressed in the dorsolateral part.

Specimen not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: corpus striatum Present
TS20: preoptic area Present
TS20: telencephalon Present Regionally restricted Expressed in the diagonal zone. Expression was low rostrally in the pallium.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory