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Gene Expression Data
Assay Details
Assay
Reference: J:206227 Wetzel-Strong SE, et al., Epicardial-derived adrenomedullin drives cardiac hyperplasia during embryogenesis. Dev Dyn. 2014 Feb;243(2):243-56
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6281969
Gene symbol: Adm
Gene name: adrenomedullin
Results
Specimen 2A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: heart Present Regionally restricted 2A , 2C Expression was detected in the epicardium with very low levels in the compact zone and trabeculae.
TS21: visceral pericardium Present Regionally restricted 2A , 2C Expression was detected in the epicardium with very low levels in the compact zone and trabeculae.

Specimen 2B: embryonic day 13.5; Admtm1Kmca/Admtm1Kmca (more )
Structure Level Pattern Image Note
TS21: heart Present Regionally restricted 2D , 2B Mutant mice showed the same expression pattern, but there was a robust and marked increase in expression level from the epicardium and trabeculae compared with wild type.
TS21: visceral pericardium Present Regionally restricted 2D , 2B Mutant mice showed the same expression pattern, but there was a robust and marked increase in expression level from the epicardium and trabeculae compared with wild type.

Specimen 2F: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: heart Present Regionally restricted 2H , 2F Expression was confirmed in epicardium by comparing to an adjacent section stained for cytokeratin, a marker of epicardium.

Specimen 7D Adm+/+: postnatal month 2 (more )
Structure Level Pattern Image Note
TS28: visceral pericardium Present 7D Adm+/+ left Expression was detected in the epicardium.

Specimen 7D Admhi/hi: postnatal month 2; Admtm1Kmca/Admtm1Kmca (more )
Structure Level Pattern Image Note
TS28: visceral pericardium Present 7D Admhi/hi left

Specimen 7D Wt1GFPCre/+;Adm3'delta/3'delta: postnatal month 2; Admtm1.1Kmca/Admtm1.1Kmca, Wt1tm1(EGFP/cre)Wtp/Wt1+ (more )
Structure Level Pattern Image Note
TS28: visceral pericardium Present 7D Wt1GFPCre/+;Adm3'delta/3'delta left Expression level in the mutant was similar to wild type littermates.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory