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Gene Expression Data
Assay Details
Assay
Reference: J:32851 Andermarcher E, et al., Co-expression of the HGF/SF and c-met genes during early mouse embryogenesis precedes reciprocal expression in adjacent tissues during organogenesis. Dev Genet. 1996;18(3):254-66
Assay type: RNA in situ
MGI Accession ID: MGI:6281712
Gene symbol: Hgf
Gene name: hepatocyte growth factor
Probe: HGF/SF cDNA2 (clone P48)
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 3A: embryonic day 9.5 (more )
Note: 25-30 somite stage
Structure Level Pattern Image Note
TS15: neural crest Present Regionally restricted 3A Expression at dorsal edge of neuroectoderm (neural tube).
TS15: 1st branchial arch mesenchyme Present 3A
TS15: 2nd branchial arch mesenchyme Present 3A
TS15: limb mesenchyme Present 3A
TS15: hindgut Absent 3A

Specimen 4A: embryonic day 9.5 (more )
Note: 25-30 somite stage
Structure Level Pattern Image Note
TS15: neural crest Present Regionally restricted 4A Expression at dorsal edge of neurectoderm (neural tube).

Specimen 4D: embryonic day 9.5 (more )
Note: 25-30 somite stage
Structure Level Pattern Image Note
TS15: branchial arch ectoderm Absent 4D

Specimen 4G: embryonic day 9.5 (more )
Note: 25-30 somite stage
Structure Level Pattern Image Note
TS15: limb mesenchyme Present 4G
TS15: limb ectoderm Present Regionally restricted 4G Authors report partial overlap in expression with c-met.

Specimen 5A: embryonic day 9.5 (more )
Note: 25-30 somite stage
Structure Level Pattern Image Note
TS15: somite Absent 5A
TS15: branchial arch artery Absent 5A No expression in arteries (i.e. dorsal aorta, arteries of branchial arches, interstitial arteries).
TS15: dorsal aorta Absent 5A No expression in arteries (i.e. dorsal aorta, arteries of branchial arches, interstitial arteries).

Specimen 6A: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: thoracic vertebral cartilage condensation Present Regionally restricted 6A Expression in area in which sclerotomic cells are condensing to form thoracic vertebral bodies.
TS21: cervical vertebral cartilage condensation Absent 6A No expression in cervical vertebral bodies or tissues that will form lumbar vertebral bodies.
TS21: lumbar vertebral cartilage condensation Absent 6A No expression in cervical vertebral bodies or tissues that will form lumbar vertebral bodies.

Specimen 7A: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: midgut Absent 7A
TS21: liver Weak Scattered 7A Expression in in a few scattered groups of cells.

Specimen E13.0 not shown: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: dorsal root ganglion Absent
TS21: lobar bronchus mesenchyme Weak Low levels of expression in mesenchyme surrounding bronchi of lungs.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory