Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Clptm1ltm1c(EUCOMM)Wtsi
Name:	CLPTM1-like; targeted mutation 1c, Wellcome Trust Sanger Institute
MGI ID:	MGI:6281108
Synonyms:	Clptm1lflox
Gene:	Clptm1l  Location: Chr13:73752125-73768724 bp, + strand  Genetic Position: Chr13, 40.12 cM
Alliance:	Clptm1ltm1c(EUCOMM)Wtsi page
IMPC:	Clptm1l gene page

Mutant Cell Line:	EPD0460_2_E07
Germline Transmission:	Earliest citation of germline transmission: J:265892
Parent Cell Line:	JM8A3.N1 (ES Cell)
Strain of Origin:	C57BL/6N-Atm1Brd
Project Collection:	EUCOMM

Allele Type:    Targeted (Conditional ready) Mutation:    Insertion     Vector: L1L2_Bact_P   Mutation details: The L1L2_Bact_P cassette was inserted at position 73753908 of Chromosome 13 upstream of the critical exon 3 (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of exon 3 at position 73754758. Exon 3 is thus flanked by loxP sites. Flp-mediated recombination removed the reporter and selection cassettes and left exon 3 floxed. (J:265892)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Clptm1l Mutation:	34 strains or lines available

Original:	J:265892 Trezise S, et al., Mining the Plasma Cell Transcriptome for Novel Cell Surface Proteins. Int J Mol Sci. 2018 Jul 24;19(8):2161
All:	1 reference(s)